Clinical Investigation About The Relevance Of Polycystic Ovarian Syndromes And The Chinese Constitution Types

Speciality:Gynecology of Chinese medicineAuthor:Yang Jun WenTutor:Associate Professor Zhou Ying[Objective]In order to investigate the relevance of chinese constitution types of patients with polycystic ovarian syndromes and normal women, analyze and summarize the predisposition to polycystic ovarian syndromes through the questionnaire scales of chinese contitution so as to provide new preach of clinical prevention, and the basis for effective measures of prevention and control.[Methods]According to the control method that the proportion of PCOS patients and normal women 2:1, research select PCOS patients in the gynecology clinic and inpatient of the First Affiliated Hospital of Guangzhou University of Chinese Medicine frome June 2010 to March 2011. At the same time, researcher choose normal women as controls. Respondents fill in the questionnaire scales of chinese constitution. Researcher statistics the results of the scales according to the criteria of chinses constitution, so as to find out the distribution of constitution types and the main pathological constitutions of the PCOS patients.[Result](1) 70 PCOS patients with an average menarche age is 13.85±1.48 years old. And the normal women, the average menarche age is 13.09±0.98 years old, both had significant differences (P<0.01).(2) The distribution of constitution types in 70 case of polycystic ovarian syndromes are as follows:qi stagnation,33 people(17.1%); damp-heat,31 people(16.1%); phlegm damp,30 people(15.5%); yang deficiency,25 people(13.0%); qi deficiency,23 people(11.9%); yin deficiency,21 people(10.9%); health,14 people(7.2%); blood stagnation,11 people(5.7%); sensitiveness,5 people(2.6%). It was discovered that qi stagnation is the maximum amount of the chinese constitution types of the polycystic ovary syndromes patients, and the least one is blood stagnation. The chinses constitution types of the polycystic ovary syndromes patients, listed in descending order, is as follow:qi stagnation, damp-heat, phlegm damp, yang deficiency, qi deficiency, yin deficiency, health, sensitiveness, blood stagnation.(3) The distribution of constitution types in 35 case of normal women are as follows:health,22 people(45.7%); qi deficiency,5 people(10.4%); yang deficiency,5 people(10.4%); yin deficiency,3 people(6.3%); phlegm damp,3 people(6.3%); damp-heat,5 people(10.4%); blood stagnation,1 people(2.1%); qi stagnation,3 people (6.3%); sensitiveness,1 people(2.1%). It is discovered that the main pathological constitution of normal women is health.(4) The comparison of the distribution of the chinese constitution types between the PCOS patients and the normal women shows that there are significant differences in health, phlegm damp, damp-heat, qi stagnation (P<0.05). And there are no significant difference in the other 5 constitutions (P>0.05)(5) The average BMI of 70 PCOS patients is 22.48±3.57kg/m2, and that of the normal women is 20.54±2.64kg/m2. There are significant differences between the PCOS patients and the normal women (P<0.01). And the proportion of overweight of the PCOS patients(25.7%) is significantly higher than that of the normal women(8.8%).[Conclusion](1)The average menarche age of the PCOS patients later than that of the normal women for nearly one year. It tell us that Polycystic ovary syndromes may disease in adolescence. So the prevention and treatment of polycystic ovarian syndromes, should be started before adolescence.(2) By clinical investigation on the chinese constitution types of the PCOS patients and the normal women, we discovere that there are significant differences between the PCOS patients and the normal women. The main pathological constitutions of the PCOS patients were phlegm damp, damp-heat and qi stagnation.(3)The onset of polycystic ovarian syndromes is relevant closely with constitutions. The constitution of patient is adjustable. Therefore the early intervention on predisposition is one of the effective means and approach to the prevention of polycystic ovarian syndromes.(4)The proportion of overweight of the PCOS patients is significantly higher than that of the normal women. Improving the constitution, reducing the incidence of obesity, is one of the effective means and approach to the prevention of polycystic ovarian syndromes.