The Endocrine And Metabolic Characteristics In Phlegm-dampness Constitution Patients Of Polycystic Ovary Syndrome

ObjectiveThrough observation of Polycystic ovary syndrome with multiple Constitution types, exploring the relationship between Constitution and syndrome in pathogenesis; and comparative analysis of phlegm-dampness Constitution and non-patients with Polycystic ovary syndrome of phlegm-dampness Constitution characteristics of their endocrine and metabolism, to adjust the constitution to provide a theoretical basis for treatment of polycystic ovary syndrome.MethodRecording the patients'menstruation, acne, hirsutism, etc., and the patient's weight, height, etc. Test the patients'fasting glucose, fasting insulin, one-hour postprandial blood glucose, two-hour postprandial blood glucose, One-hour postprandial insulin, Two-hour postprandial insulin, calculate the patients'body mass index, insulin sensitivity index. Using statistical software to data and information collected for statistical analysis. Observed in patients with Polycystic ovary syndrome, the proportion of phlegm-dampness constitution. Exploring the relationship between Constitution and syndrome in pathogenesis; and comparative analysis of phlegm-dampness Constitution and non-patients with Polycystic ovary syndrome of phlegm-dampness Constitution characteristics of their endocrine and metabolism.Result1,The common clinical manifestations of polycystic ovary syndrome with menstrual disorders and infertility-based, followed by obesity;2,Physical distribution:Constitution were 25 cases of phlegm-dampness, accounting for 41.67%; 3,Constitution and syndrome in pathogenesis of Polycystic Ovary Syndrome: In 25 patients with Polycystic ovary syndrome of phlegm-dampness Constitution,22 cases of syndrome of phlegm-dampness, accounting for 88%,2 cases of syndrome of Kidney, accounting for 8%,1 cases of syndrome of blood stasis, accounting for 4%, Syndrome of phlegm-dampness with kidney and blood stasis in the incidence increased significantly compared, and the difference is Significant statistical significance (P<0.01);In 35 patients with non-phlegm-dampness constitution,21 cases of syndrome of Liver-Qi stagnation, accounting for 60%,11 cases of syndrome of Kidney, accounting for 34.29%, cases of syndrome of blood stasis, accounting for 8.57%, the Liver-Qi stagnation syndrome rate is higher than blood stasis syndrome rate, and the difference is statistically significant (P<0.05); the Kidney syndrome rate is higher than blood stasis syndrome rate, and the difference is statistically significant (P<0.05);4,The incidence of obesity:In 25 patients with Polycystic ovary syndrome of phlegm-dampness Constitution, obesity in 21 cases,84%,35 patients with non-phlegm-dampness constitution, obesity 2, accounting for 5.71%. Phlegm-dampness constitution group and non-Phlegm-dampness constitution group, significantly higher incidence of obesity, and the difference is Significant statistical significance (P<0.01);5,B-ultrasonography:in 25 patients with phlegm-dampness Constitution PCOS Polycystic sample changer for b-22,88% of the total Group of phlegm-dampness Constitution,35 cases of phlegm-dampness Constitution in PCOS patients with b-ultrasound for 25 cases of cystic changes, accounting for non-group of phlegm-dampness Constitution 71.43%. Phlegm-dampness Constitution group compared with the non-phlegm-dampness Constitution group, b-more obvious rise in the incidence of cystic changes, the difference is no statistically significant (P>0.05);6,Endocrine hormone index:phlegm-dampness Constitution group compared with the non-phlegm-dampness Constitution group, phlegm-dampness Constitution group effect of luteinizing (LH) levels and serum testosterone (t) lower average water, differences are statistically significant (P<0.05);7,Indicators of glucose metabolism:phlegm-dampness constitution and non-phlegm-dampness constitution group compared fasting insulin phlegm-dampness constitution group (FINS) level, body mass index (BMI) were higher, while insulin sensitivity index (ISI) is low, and significant differences are Significant statistical significance (P<0.01); according to the formula and the relevant diagnostic criteria, the results also suggest:phlegm-dampness constitution and non-phlegm-dampness constitution group compared, phlegm body insulin resistance in patients (IR), There were significant differences of Significant statistical significance (P<0.01); impaired glucose tolerance (IGT) higher incidence, the difference was statistically significant (P <0.05).Conclusion1,Through the investigation and study, thought the phlegm-dampness constitution is PCOS sends the physique much.2,In the patiens of PCOS, phlegm-dampness constitution easily lead to phlegm-dampness syndrome, Liver-Qi stagnation syndrome and kidney syndrome are likely to non-phlegm-dampness constitution.3,PCOS patients with phlegm-dampness constitution to obesity, HI, IR and IGT as the main performance; non phlegm-dampness constitution to hyperandrogenism hyperinsulinemia and high LH based, in part associated with obesity, HI, IR and IGT.