Comparison Between The DWI Imaging Features And Pathology Of Hepatic Alveolar Echinococcosis

Purpose:To observe the imaging features of MR DWI in hepatic alveolar echinococcosis (HAE) and analyze the correlation between MR-DWI parameters Apparent diffusion coefficient (ADC) values HAE and microvessle density (MVD), and to investigate the clinical value of ADC values for evaluating the pathological feature of HAE. Methods:26 cases with HAE underwent routine MR scan plus MR-DWI imaging sequence. The ADC values of the center, the peripheral zone and the around area of lesion were measured with the liver DWI analysis software. Comparison of the imaging and operative specimen histological feature were made. The correlation between ADC values parameters and MVD of the lesion were analyzed (a=0.05). Results:There was statistically significant difference among the groups of the center, the peripheral zone and the around liver tissue of ADC values of 26 patients with 32 lesions (F=16.81,31.02, P< 0.05). No correlation was found between the ADC values of peripheral zone of lesion and MVD (P=0.864,0.753). Conclusion:MR-DWI images can reflect the heteromorphism of peripheral zone and help to identify the infiltration area and biological boundary; No relations were shown between the ADC values of peripheral zone of lesion and MVD.