The Clinical Research Of Cerebral Aneurysms Treated With Hydrocoils In Combination With Platinum Coils

Objective:To retrospectively compare and analysis the 51 cerebral aneurysms'clinical data with endovascular embolization treatment, to evaluate the efficacy of cerebral aneurysms treated with hydrocoils in combination with platinum coils and the cost of surgery.Methods:Retrospective analysis was performed of 51 cerebral aneurysms treated with endovascular coil occlusion in our hospital from January 2007 to December 2010.25 aneurysms (Hydrocoil group) embolized using Hydrocoil in combination with platinum coils were compared with 26 volume-shape-matched aneurysms (platinum coils group) treated only with platinum coils. Patient characteristics, including age, sexuality, preoperative Hunt-Hess grade and the location and size of each aneurysm were documented. The aneurysms occlusion degree, packing attenuation, surgery cost and coils used, surgery-related complications, clinical and angiography were collected and analyzed by statistics.Results:The patients'demographics and the aneurysms'characteristics between the two group were comparable (P>0.05). No significant difference was found between the complete obliteration of Hydrocoil group and platinum group (76% versus 53.8%, P>0.05). Hydrocoil group yielded significantly greater packing attenuation (69.2% versus 30.8%, P<0.05). With the aneurysm volume increased, the packing attenuation of two groups decreased (P<0.05). The average surgery cost and coils used between the two groups were no statistically significant, but the average surgery cost of Hydrocoil group was higher than platinum group (RMB 92344.0 versus RMB 86257.7). (5) Hydrocoil group had a similar complication rates with platinum group (15.0% versus 15.3%, P>0.05). (6) There was no statistically significant comparing the recurrence rate of Hydrocoil group and platinum group (6.7% versus 21.4%), because of insufficient sample. (7) No statistically significant difference was found between the two groups'independent survival at half of a year (P>0.05).Conclusion:Endovascular embolization of cerebral aneurysms with hydrocoil combined platinum coils is safe and feasible. Endovascular treatment of cerebral aneurysms with Hydrocoil in combination with platinum coils increases the packing attenuation compared with platinum coils with similar complication rates, but the cost doesn't reduce. The long-term efficacy is required further research.