Bushenzhuanggu Treating Kidney Deficiency Knee Osteoarthritis Clinical Observation

Background:China's aging society in 1999, all in the increased incidence ofage-related diseases, including osteoarthritis of the knee(Osteoarthritis, OA) significantly increased the incidence, the current quality of life of older persons has become one of most common orthopedic Disease, caused by the orthopedic industrywide attention. Knee osteoarthritis is a slow, gradual process, the acute exacerbation and remission alternating each other, acuteexacerbation of the pain, swelling, stiffness, deformity and dysfunction as the main performance. The main clinical treatmentto relieve symptoms and improve function for the purpose of theapplication in which drug treatment is common. Western medicineto anti-inflammatory analgesics as the gold standard, but in recent years, the side effects found in the medical profession gradually, such as gastrointestinal ulcers, renal function, cardiovascular risk, etc., limits its clinical use. Internal medicine therapy on the efficacy of knee osteoarthritis in the country have been positive, especiallybecause of its fewer side effects, focusing on individualizeddiagnosis and treatment and to be more widely used. Countrybased on the medical understanding of disease pathogenesis, based on the proposed side Bushenzhuanggu soup, kidney andstrengthening the foundation, the clinical effect is significant. But their clinical efficacy is still a lack of evaluation of clinical systems.Purpose:Observation and Treatment of kidney deficiency Bushenzhuangguknee osteoarthritis clinical efficacy.Patientsand Methods:Select the hospital outpatient and inpatient rheumatology 60 patients with knee osteoarthritis, using randomized controlledclinical trial methods, choose a simple oral treatmentBushenzhuanggu Tang,30 patients with simply using Western non-steroidal anti-inflammatory drugs The control group for 4 weeks, the use of American Society of Knee Surgery knee score (KneeSocietyScore, KSS) and visual analogue scale (VisualAnalogueScales, VAS) evaluation before and after treatmentscores were compared using statistical methods. Statistics bySPSS13.0 package before and after the data were comparedusing t test.Results:The treatment group KSS clinical scores before and after treatment, compared to before treatment and after treatment, the degree of knee pain treatment and control groups were significantly different (P<0.01), after treatment, no significant difference between the two groups. Activity and stability of the treatment group is different before and after treatment (P <0.05), no significant difference between the control group, there are differences between the two groups (P<0.05). Comparing the total score, the treatment group before and after treatment were significantly different (P <0.01), differences between the control group (P<0.05), there are differences between the two groups (P<0.05). The treatment group KSS function score were treated before and after treatment, walking scores in the treatment group had significantly (P<0.01), differences between the control group (P<0.05). After treatment, there are differences between the two groups (P<0.05). Up and down stairs score in the treatment group is different before and after treatment (P<0.05), no significant difference between the control group, there are differences between the two groups (P<0.05). Comparing the total score, the treatment group before and after treatment between the treatment group compared (P<0.05), there are differences between the two groups (P <0.05). After treatment, both groups improved pain patients, the treatment group in the activity, stability and function improved significantly, indicating Bushenzhuanggu treating kidney deficiency osteoarthritis of the knee in patients with knee pain relief, particularly In improving the efficacy of knee function is accurate. In addition, the treatment group and control group 4 weeks after treatment VAS scores showed no significant difference (P> 0.05), that Bushenzhuanggu soup and non-steroidal anti-inflammatory drugs in efficacy was not significant.Evaluation of syndromes in traditional Chinese medicine, the treatment group, the total effective rate was 86.67%,6.67% with the control group there were significant differences, indicating Bushenzhuanggu soup kidney deficiency can significantly improve the clinical symptoms of knee osteoarthritis.Conclusions:Bushenzhuanggu treating kidney deficiency relief in knee osteoarthritis patients with knee pain and improve knee function in patients, with non-steroidal anti-inflammatory drugs in the treatment of kidney deficiency type of knee osteoarthritis efficacy of 4 weeks Are effective on the activity, stability and functional improvement Bushenzhuanggu soup is more effective. Clinical Evaluation of TCM, Bushenzhuanggu soup kidney deficiency can significantly improve the clinical symptoms of knee osteoarthritis, with the control group there were significant differences.