Comparative Study On Underwent Laparoscopic And Underwent Retropubic Radical Prostatectomy

Objective: To compare and study the treatment efficacy between laparoscopic radical prostatectomy and open retropubic radical prostatectomy as the treatment of localized prostate cancer.Methods : The clinical data of 8 cases of patients underwent laparoscopic radical prostatectomy and 12 cases of patients underwent open retropubic radical prostastectomy were analyzed retrospectively at our hospital between June 2005 and June 2010.20 cases were all diagnosed as prostate cancer by Pathology through prostate biopsy before operation. Indexes of operating time, bleeding volume during operation, the duration of catheterization, hospitalization stay after operation were compared.Results :8 cases of patients underwent laparoscopic radical prostatectomy were all successfully performed. No patient was converted to open surgery. The mean operating time of LRP group were (246.50±88.58)minutes. There was statistical difference between the RRT group which mean operating time was (164.75±38.04) minutes (P<0.05) . The mean bleeding volume during operation, the duration of catheterization, hospitalization stay after operation between LRP group and RRP group were (356.63±153.89) ml(P<0.05) and (892.33±383.08)ml (P<0.05); (13.25±3.99) days and(18.83±3.10) days (P< 0.05); (17.71±4.10) days and(21.33±2.87) days (P< 0.05),respectively. All 8 patients underwent LRP were followed up 2 years. The one-year biochemical recurrence rate was 12.5%(1/8),the two-year biochemical recurrence rate was 25%(2/8) ; the six-month continence rate was 37.5%(3/8);the one-year continence rate was 87.5%(7/8); one cases were dead. All 12 patients underwent RRP were followed up 2 years. The one-year biochemical recurrence rate was 16.7%(2/12), the two-year biochemical recurrence rate was 25%(3/12); the six-month continence rate was 41.7%(5/12);the one-year continence rate was 83.3%(10/12);two cases were dead.Conclusion:Laparoscopic radical prostatectomy not only perform less blood loss and faster recovery, but also play the similar functional results compared with open retropubic radical prostatectomy. So LRP should be promoted as a better treatment methods for localized prostate cancer.