The ~1HMRS And DWI Study Of AIDS With Toxoplasmic Encephalitis

Objective:To investigate magnetic resonance spectrum (1H-MRS) and diffusion weighted imaging (DWI) features of AIDS concurrent toxoplasma encephalitis. Methods: Analysis magnetic resonance spectrum and magnetic resonance imaging (DWI) diffusion weighted characteristics of 11 patients diagnosed AIDS concurrent toxoplasma encephalitis. Results:From brain lesions necrotic area to contralateral normal area, by the metabolites ratio statistics analysis, solid area of lesions and the contralateral normal area have significant statistical difference on NAA/Cr value. Compared the NAA/Cho value of near normal area and necrotic area, solid area, edema area,there were significant differences. The (Cho+MI)/Cr ratio of necrotic area have significant difference statistically, compared with near normal area and the contralateral area. There are also significantly statistical difference between normal solid area and near normal area, the contralateral normal on (Cho+MI)/Cr ratio. Analysis ADC values of lesions and contralateral normal area, it generally elevate from lesion's necrotic area, solid zones to edema area. By statistical analysis, the difference between contralateral normal tissues and solid region, edema area have statistical significance, the same as necrotic area and edema area. Conclusion:Magnetic resonance spectrum provide metabolic information for diagnosis of toxoplasma encephalitis. DWI sequences help were encephalitis staging and level diagnosis, but the absolute ADC value of the lesion can not be used as the diagnosis evidence of toxoplasma encephalitis, and it also can not be used to distinguish the two disease.