| BackgroudIn recent years, with the development of china economy , people's living environment,work manner,psychological adjustment ability have great changes. With the quickening pace of people's lives, competitive pressure and psychological pressure of people in all walks of life also grow gradually, various kinds of psychological problems are appearing. Currently, domestic and international researches show that the prevalence of mental disorders significantly increased over the past ten years ,and different crowds show different problems.There was a certain relationship between the incidence of mental disorders and demographic factors (such as gender, age, marital status, region, education, economic status, working condition, etc.) ,and comorbidity was found among mental illness . However, for different survey sites and survey tools,the prevalences of mental illness varied widely,and this could influence the comparability among prevalence of various mental disorders.As a tool for epidemiological investigation of mental illness, after several cross-cultural testing and repeated amendments,composite International Diagnostic Interview Checklist (Composite International Diagnostic Interview Composite, CIDI) ,had good cultural adaptability , and with being used in many countries ,it has good reliability and validity.As a survey tool, CIDI-3.0 was consistent with chinese cultural characteristics , and after evaluation of their reliability and validity,experts found that it had good criterion validity and satisfactory test-retest reliability, screening part with high sensitivity, diagnostic part with high specificity,it could be used as a screening and diagnostic tool in epidemiological studies of mental illness.For great Inter-city differences in prevalence rates of mental illness in Zhongshan, Shenzhen, Dongguan locating in zhujiang economic Zone , so what was the prevalence of mental illness in Guangzhou which locatigng in the heart in the zhujiang economic Zone ? How did the demographic factors influence the prevalence of mental illness ? Therefore, we used the chinese version of CIDI-3.0 survey instruments to understand these status by epidemiological method by surveying the resident population in Guangzhou.ObjectiveTo survey different types of mental illness prevalence, distribution about 16 years and over in Guangzhou permanent residence ; understand characteristics of the social demographic factors (gender, age, marital status, region, education level, economic status, work status, etc.) and the social demographic factors' impact to mental illness ; understand the status of comorbidity of mental disorders.MethodsOct 12, 2009 -Jan 3,2010 ,to investigate urban and rural 2707 residents with 16 to 84 years in the six districts of Guangzhou ,using the Composite International Diagnostic Checklist Chinese version 3.0 (CIDI 3.0) as a tool ,by stratified random sampling method.Result(1) Mental illness prevalence survey data and case:①The number of mental illness investigations should check 3293 people,and it was completed in 2707 investigated persons (82.21%). The completion of the survey respondents: age 16 to 84 years, mean (40.3±15.2) years; male 1300(48.02%), female 1407 people (51.98%);City 1902 people (70.3%),village 805 people(29.7%). 586 residents (17.79%) were dropout, mainly due to people working (400, 68.26%), traveling (107, 18.26%), seeing a doctor (21, 3.58%) or refusal (58, 9.90%).②Rates of mental illness for 4 weeks (time point), 12 months and lifetime standardized prevalence were 1.69%, 3.89% and 7.61%.In the standardized point prevalence, the top five of special phobia (0.54%), intermittent explosive disorder (0.29%),major depressive disorder (0.23%),alcohol use disorder,(0.16%), obsessive-compulsive disorder(0.14%);In the standardized lifetime prevalence, the top five were major depressive disorder (2.25%), special phobia (0.95%), intermittent explosive disorder (0.93%),alcohol use disorder (0.92%), non-specific depression (0.62%).(2) Differences of the prevalence of mental illness among sex groups or urban and rural groups: ①Standardized lifetime prevalence rate in various types of mental disorders was significantly higher in female than in male (8.39% VS 6.23%,χ~2 =4.61,p=0.032).②Lifetime prevalence of major depressive disorder was higher in urban than rural areas, in female than in male (2.68% VS 1.49%,χ~2=3.53,p=0.06; 2.99% VS 1.62%,χ~2=5.58,p=0.018);lifetime prevalence of drugs use disorders was higher in rural than in urban,in male than in female (0.39% VS 0.05,χ~2=2.06,p=0.047; 0.31% VS 0,χ~2= 4.34, p = 0.037); lifetime prevalence rates of post-traumatic stress disorder was higher in female than in male (0.50% VS 0,χ~2=4.7,p=0.03), lifetime prevalence of alcohol use disorders was higher in male than female (1.39% VS 0.28%,χ~2=10.15,p=0.001).(3) Demographic data of mental illness the differences of the prevalence rates among demographic factors:①Prevalence rates of primary (10.03%), junior high school (9.04%) were high than senior middle schooll group (6.29%), college and university (6.08%) group, the difference was statistically significant(χ~2=9.52,p=0.049).②Prevalence rates of unemploymentor,laid-off persons(11.87%), students (9.38%),retirees (7.59%),domestic workers (7.75%) were higher than formal workers (6.08%) group, the difference was not statistically significant(χ~2=10.27,p=0.114). But there was a significant difference about prevalence rates between unemploymentor,laid-off persons and formal workers(χ~2 =9.63,p=0.002).③Prevalence rates of very poor (16.33%) and poor (10.37%) were higher than normal level (5.28%) and the wealthy (7.11%) group, the difference was statistically significant (χ~2=16.93,p=0.001).④Prevalence rate of divorce,separation (24.49%) and widowed (19.10%) was higher than married (5.46%) group, the difference was statistically significant (χ~2 =43.54,p=0.000).(4) Comorbidity of mental illness:①There were single diagnosed 135 cases of mental disorders in 231 people (90%) with lifetime prevalence , and 40 cases had double- diagnose , 24 cases had tri-diagnose.②Major depressive disorder was comorbid with alcohol use disorder, special phobia, post-traumatic stress disorder,social phobia, intermittent explosive disorder, and anxiety disorder had comorbidities with panic disorder, obsessive compulsive disorder, social phobia, specific phobia . Conclusion(1) The rate of total mental illness standardized lifetime prevalence is 7.61%, female prevalence rate is higher than that in males(2) Low education, poverty, divorce, widowed had higher prevalence of mental illness.(3) We found that the mental disorders with comorbidities in community which are more common in patients with depression and anxiety disorders.
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