Relationship Between Cervical Spondylosis Myelopathe And Serum Levels Of VitaminB12 And Folic Acid

Objective:To find out the serum levels of VitaminB12 and Folic acid, and explore the relationship between cervical spondylosis myelopathe and serum levels of Vitamin B12 and Folic acid. Methods:Collecting data of the serum levels of folic acid and vitamin B12 in 111 patients of cervical spondylosis, separating the patient to groups according to the image presentation,bearing grade and the course. Carrying on the groups to comparison research. Results:1) The serum levels of folic acid and the Vitamin B12 of cervical spondylosis myelopathe patients who presenting MRI T2 high spine signal(ISI) is lower than the non-high signal group equally (P<0.05).2)The distribution of ISI of spinal cord mild bearing grade group and the serious group is not obvious different (P>0.05).3) The serum levels of Vitamin B12 of cervical spondylosis myelopathe patients who present MRI T2 high spine signal(ISI) and no obvious compression is lowest while in who present no MRI T2 high spine signal(ISI) but obvious compression is highest in groups;4) Cervical spondylosis myelopathe patients who presenting MRI T2 high spine signal (ISI) have shorter courses than the non-high signal patients. Conclusions:Lack of VitaminB12 and the folic acid is a risk factor of the cervical spondylosis myelopathe and make a promoting or cooperating effect in the pathogenesis of the cervical spondylosis. Further researches will provide certain theory basis for prevention and treatment of the cervical spondylosis.