Study Of The Prostate With Cross-sectional Anatomy And MRI

Objective:Using magnetic resonance imaging (MRI) to quantitatively research prostate in each age section of normal person and 6 specimens, analyze the MRI changes of indicators of the whole prostate in the corpses and people alive, and then the corpses made series plans by using collodion embedding method. We analyzed the anatomy characteristic of the pelvic cavity region in the collodion-embedded plans, and compared with the MRI of normal people. The changes of indicators of the central zone diameter line and volume were valued which could provide anatomy data for the imaging, we also explore the prostate imaging characteristics and evolution with ageing.Methods:1. The MRI study of the prostate in specimen:6 male corpses fixed by 10% formalin which without prostate related disease, were selected to make MRI scan in axial, oblique, sagittal section. We view the boundary of the prostate's zone.2. The anatomy study of the prostate in specimens:6 male corpses fixed by 10% formalin were selected, and then divided into 3 groups random,250μm -270μm collodion-embedded plans were made in axial, oblique, sagittal section.3. The MRI study of the prostate in people:684 volunteers, who without prostate related disease, they aged from 20 to 79, and divided into 5 groups according to the age:MRI signal intensity and characteristic with aging of the prostate were observed.4. A comparative study between cross-sectional anatomy and MRI of prostate zone: there are three basic cross-section:sagittal section (central), axial section (superior level, level of verumontanum, low level), oblique section (through the section of long axis in urethra and ejaculatory duct), to observe detailed characteristic.5. MRI study on ageing prostate. The contents of observation and measurement included the prostate's MRI signal intensity and characteristic with aging; To survey the diameter line of prostate and volume, Set up the reference range of the normal prostate diameter, the volume and to analyze its characteristics.Results:1,MRI changes of indicators of the whole prostate zone in the corpses Whole prostate of corpses show low signal in T1WI; Representation of different corpses prostate zone same as alive in T2WI. Periphery zone of prostate showed high signal, central zone show low signal.2,Indicators of the whole prostate zone in the corpses of plansRecognize periphery zone,central zone, transitional zone, paraurethral gland zone and fibrous muscle zone on the basis of slice, but their bounds are not obvious.3,MRI changes of indicators of the whole prostate zone alivePeriphery zone of alive prostate show high signal, and higher than central zone; central zone show low signal. Only show outline of prostate in T1WI, each zone shows eaque or low signal, and not to distinguish further.4,A comparative study between cross-sectional anatomy and MRI of prostate zone: there are three basic cross-section:sagittal section (central), axial section (superior level, level of verumontanum, lower level), oblique section (through the section of long axis in urethra and ejaculatory duct), to observe detailed characteristic.5,The results of diameter line and volume statisticsAbout the scope of the overall volume of the prostate is (11.59～47.01cm3), Its upper and lower tracks, before and after the trail, trail around the volume increases with age, There were significant difference in various age groups(P<0.05). volume of prostatic central zone is (2.89～12.46cm3). Its upper and lower tracks, before and after the trail, trail around the volume increases with age, volume percentage of the total volume of the prostate accounted for (22%～36%), Its proportion increase with age (P<0.05).Conclusion:(1)Boundary line of different zones can be divided in every section.(2)Prostate zone's signal of MRI is same between corpses and alive.(3)A comparative study between cross-sectional anatomy and magnetic resonance imaging of prostate zone. (4) The diameter line,volume of prostate gland and volume of the whole prostate grows gradually following increase of age. The diameter line,volume of central zone and volume of central zone to prostate proportion grows gradually following increase of age.