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Quantitative Research For Pneumoconiosis Micronodular Examined By Multislice Spiral CT

Posted on:2011-08-02Degree:MasterType:Thesis
Country:ChinaCandidate:Y H XiaoFull Text:PDF
GTID:2154360308484559Subject:Medical imaging and nuclear medicine
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PART I COMPARATIVE STUDY BETWEEN THE MAXIMUM INTENSITY PROJECTION OF MULTISLICE SPIRAL CT AND THE SMALL SHADOW EXAMINED BY TRADITIONAL HIGH KV RADIOGRAPHYObjective: to compare the reconstructed radiography of the maximum intensity projection (MIP) in coronal view of multislice spiral CT and the examination results from the patients with non-dusty lung in 0 stage by high KV radiography. Methods: Eighteen patients with non-dusty lung in 0 stage accept the scan of conventional radiation doses of multislice spiral chest CT. The thick of layer is 5mm, the reconstructed interval is 5 mm, the reconstructed lamella by standard algorithm is 0.625mm, and the reconstructed maximum intensity projection (MIP) images in coronal view of multislice spiral CT is 7.5mm. Two senior physicians read the MIP images and the high KV radiography, interpret the results by nodule, likely nodule, suspected nodule or no nodule, compare the results from MSCT MIP images with these from the small shadows, examined by high KV radiography, of patients with non-dusty lung in 0 stage, and make analysis. Results: 1081 micronodulars by multislice spiral CT images have been checked out for the eighteen patients, 60.1 pieces per capita on average. However, 312 small shadows by high KV radiography have been checked out, 17.3 pieces per capita on average. The ratio of micronodular checked out by the MIP images of multislice spiral CT is apparently higher than the traditional high KV radiography, and the difference has statistical significance (P<0.05). Conclusions: The legible ratio by multislice spiral CT is apparently higher than those by traditional high KV radiography and the focus display is also obvious and clear. It is significant to clinical application on early pneumonoconiosis diagnosis and division of stages. PART II STUDY OF THE QUANTITIES OF PNEUMONOCONIOSIS MICRONODULAR EXAMINED BY MAXIMUM INTENSITY PROJECTION OF DIFFERENT SLAB THICKNESS OF MULTISLICE SPIRAL CTObjective This article aims to explore the quantities of pneumonoconiosis micronodular examined by maximum intensity projection (MIP) in coronal view of different slab thickness of multislice spiral CT (MSCT). Method forty-five male patients, 46.7-year-old on average and 13.9 years'dusty occupation on average, with pneumonoconiosis in stage I, examined by Chongqing occupation disease prevention and treatment center during 2008 Nov. to 2009 May, are chose to accept the conventional scan of multislice spiral CT (MSCT). 0.625mm thick of thin-slab-image is reconstructed by standard algorithm, the data is transferred to work station ADW4.2 by DICM format, and 20mm thick of volumetric data in right lung field on the basis of the upper edge of aortic arch are used to analyze. The volumetric data are divided into two 10mm slide crossing MIP visulization image, and the thoracic cage and the mediastinum structure are wiped off along subpleura. Count the nodules found in the two images and the data obtained will be regarded as the standard. Project the selected volumetric data by maximum intensity projection (MIP) in coronal view of 3mm, 5mm, 8mm and 10mm, interpret the results by nodule, likely nodule, suspected nodule or no nodule, and the first two are regarded as nodule detecte and last two are regarded as no nodule detecte. Results Micronodules detected by crossing and 3mm, 5mm, 8mm and 10mm of MIP images are respectively 6705, 9023, 6953, 5200 and 4561. The difference of slab thickness of 5mm thick has no statistics significance byχ2 examination (χ2=0.6339,P>0.01), and the other three types of difference has statistics significance (χ2=44.5060,657.6827,844.3803,P<0.01)on a basis of quantities detected by crossing examination. Conclusion 5mm thick MIP images have less overlap, focuses are clearer and pneumonoconiosis micronodular are the most objective.
Keywords/Search Tags:pneumonoconiosis, multislice spiral computed tomography, maximum intensity projection, multislice spiral CT, pneumonoconiosis, micronodular
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