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Research Of Coronary Heart Disease Combines Type 2 Diabetes Mellitus Of TCM Discriminating Mark Of Types And Relationship Whith The Correlativity Between Blood Vessel Bast Function Extent Of Damage

Posted on:2011-11-28Degree:MasterType:Thesis
Country:ChinaCandidate:D K WuFull Text:PDF
GTID:2154360308972637Subject:Chinese medicine
Abstract/Summary:PDF Full Text Request
Type2 Diabetic Mellitus(T2DM) and Coronary Heart Disease(CHD) both belonged to metabolic disease, they had lots of common risk factors, sueh as hypertension dysliPidemia,blood hyPereoagulativestate,hyperinsulinemia(HINS),obesityet etc, which were just the same risk factors of atheroslerosis.Numerous reasearehes showed that HINS was the"common soil" that could lead to series of metabolic diseases, like DM and CHD.The Produet effete of DM with CHD accelerated the Progression of atheroselerosis.Therefore,Natinonal Cholesterol Edueation Program(NCEP) adult treatment third report(ATPⅢ)ranked DM as the equivalent risk of CHD.The morbidity of DM was growing at anannual rate of 30-40 million Per year.Besides, more and more young People were suffering from it.With the inereasing mortality, DM with CHD had been a serious threaten to modern human,both inquality and safety of life.Traditional Chinese medieine(TCM)had not proposed the name of the disease,but separately dicoused symptoms and treatments in the following categories, for example Xiao Ke,obestrcution of Qi in chest,Angina Pectoris and Heart- throb etc. After that, combined with modern research methods and clinieal experience summary,Latter traditional Chinese medicine doctors put forward some new disease names, such as TangXin disease,Xiao Xin disease XiaoKe-obestrcution of Qi in the chest.AT the same time the further Pathogenesis had been realized.They considered that the main reasons were naturalendowment insuffieioney,Post-natal improper diet,excessive comfort and lack of exereise, Plus the invasion of exogenous pathogenic factors, So called with inate deficieney aequied los tsupport.Moreover Phlegmand and blood stasis were the main Pathogenie Produets, which accelerated the disease Progression. In clinieal treatment, combination of disease differentiation and syndrome differentiation was the most important method, the former was Premise, the latter was core.The haekneyed syndromes were Qi-Yin defieiene,Fire excess from Yin defieiney, Qi stagnation and blood stasis, Phlegm dampness and blood stagnation, accumulation of cold and blood stasis, cardic-splenic insuffieieney of Yang etc.Modern medicine demonstrates coronary heart disease morbidity and the lipid are soaked, the blood platelet is accumulated with thrombopoiesis, the oxygen free radical is come into being, the blood vessel bast function is derided, infection and scorching reaction go hand in hand. Dysfunction relation is close especially the narrow pulse correlativity studying the paroxysm and crown discovering, crowning impatient incomplete pulse blood with in recent years dispatches, but with bast. Blood vessel bast function damage is already affirmed for independent important dangerous coronary heart disease factor. So far, coronary heart disease combines Type 2 diabetes mellitus of TCM discriminating mark of type and the correlativity between blood vessel bast function extent of damage gets in touch with, the go into still being short of a pertinency proves that, therefore, the coronary heart disease combines Type 2 diabetes mellitus of traditional Chinese medicine discriminates mark of type and functional correlativity of blood vessel bast relation is in progress to coronary heart disease to study to have very important significance. PurposeTo research whether coronary heart disease combines Type 2 diabetes mellitus of TCM discriminating mark of type have relationship whith the correlativity between blood vessel bast function extent of damage.Research methodIndex studying four examine information and the relevance laboratory of TCM of 127 patients, with collected data entry EpiData3.10 building a data base, statistic analysis data leading-in Spss 13.0 is carried out, syndrome groups of TCM preparation by screening adopt system clustering two step clustering law in analysing, again be tied in wedlock "the PRC national standard of TCM diagnoses the technical term syndrome part clinically" decides each the representative symptom being allotted a type kind, sum up in TCM certificate type, and analysing the objective data being unlike the certificate type compared.Research result1.2-DM combins CHD can be Divided to 3 types symptoms of TCM:Qi-Yin defieiene,Qi defieiene and Phlegm stasis,Yang defieiene and blood stasis.2.Stssis is the main factors of the 3 types symptoms of TCM.3.In groups suffering 2-DM combins CHD, the level of ET of Qi defieiene and Phlegm stasis is higher than it of other 2 types。The level of NO has no differentence in the 3 types, neither SOD。...
Keywords/Search Tags:Type 2 Diabetes Mellitus, Coronary Heart Disease, cluster analysis method, TCM type of syndrome
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