Erythema Broth Treatment Of Systemic Lupus Erythematosus Clinical Research

Objective:To observe the treatment of systemic lupus erythematosus broth side experience side effects. Comparison of Integrated Traditional and Western Medicine with a simple difference in the efficacy of treatment of systemic lupus erythematosus, the clinical development of safe and effective treatment of Integrative Medicine to provide the basis to guide its clinical application.Methods:the cases of sources for wuhan first hospital ward of the outpatient department and rheumatism 39 sle patients, ChiCheng toxic heat for TCM dialectical type, diagnostic for sle, belong to light, medium activists. According to the doctor order randomly divided into treatment group and control group, the treatment group and control group,18 cases. Patient:treatment group shall maintain the west heal party, and share erythema consomme decoction (two flowers cane 15g scutellaria baicalensis 18g sophora flavescens 15g 9g snake tongue grass 30g gypsum 12g desertliving 18g origin,15g licorice 6g, altogether, sooner or later, a) portion. In the west, maintaining patients to heal party unchanged. After the illness gradually alleviate to maintain law reduced hormone. According to the illness and calcium, anti-inflammatory, shall protect stomach support treatment with hypertension and diabetes, those given step-down, oral glucose-lowering drugs. Observation is the two groups of disease activity index, TCM clinical curative effect, laboratory, reduce the dosage of hormone withdrawal and adverse reaction.Results:(1) in the treatment group,21 cases of clinical remission in 3 cases, 7 cases were markedly effective in 9 cases,2 cases ineffective, the total effective rate was 90.48%; the control group,18 patients in clinical remission in 1 case,5 cases markedly effective in 6 cases 6 cases, total effective rate was 66.67%. Statistically, the difference between two groups (P<0.05). Prompt treatment group than the control group.(2) treatment group before and after the symptom scores were significantly different, P<0.05; control group before and after treatment symptom scores were significantly different, P<0.05; After treatment, symptom scores were significantly different the efficacy of the treatment group than the control group, P<0.05.(3) before and after treatment of lupus activity index score was significant difference, P<0.05; control group before and after treatment of lupus activity index score was significant difference, P<0.05; After treatment of lupus activity index score significantly difference in the efficacy of the treatment group than the control group, P<0.05.(4) treatment group and control group compared before and after the treatment that laboratory after treatment group and control Group can improve SLE laboratory (P< 0.05), the treatment group, and improve the WBC PLT CRP, C3, ESR and proteinuria is better than control group, the comparison between the two groups have significant difference (P< 0.05),(5) before the treatment group prednisone dosage no significant difference (p> 0.05, Before and after the treatment of two groups prednisone dosage was significant difference (P< 0.05, The treatment group and control group dosage of prednisone with significant difference (P< 0.05). The treatment group than in control group on the hormone withdrawal.(6) two groups in treatment process, the treatment group 1 cases occur secondary infection,5 cases occur secondary infection. Two groups in general infection rate compared with significant difference (P< 0.05). In treatment group than controls infection rates.Conclusion:1, the treatment group (erythema of western medicine therapy share the clear) and control group (original) therapy of western medicine therapy methods ChiCheng toxic heat of systemic lupus erythematosus (sle) in different degree, and the total curative effect is significantly better than efficient.2, the treatment group (erythema of western medicine therapy share the clear) and control group (original western medicine therapy) in improving clinical symptoms, reduce lupus activity index, improving laboratory (leukocytes, platelets and CRP, albuminuria, C3, and promote hormone ESR shut down and reduce adverse effect is more significant aspects.