| Objective To evaluate the clinical curative effect and security of transurethral plasmakinetic vaporize resection of prostate(PKRP) and transurethral resection of prostate(TURP) in the treatment of symptomatic benign prostatic hyperplasia(BPH).Methods This project was study at the department of Urology of Second Affiliated Hospital of Nanchang University From Mar 2008 to Nov,73 patients who were diagnosised BPH served as TURP group,All 73 patients accepted TURP treatment;and from Dec 2008 to Nov 2009 in the same unit,other 107 patient with BPH as a PKRP group,they accepted PKRP treatment.The two groups patients according the same inclusion and exclusion criteria,Preoperative detect PSA value,ultrasonic measure prostatic size,find out there other diseases of urinary system,uroflometry,Digital rectal examination to check for nodules and the characteristics of the prostate gland, and other routine examinations.Observed two groups of patients with operative time, bleeding volume,overoperative changes in serum sodium and blood glucose,preoperative and postoperative 1 month of IPSS,RUV,Qmax,QOL,and observation of surgical operative complications and prognosis,etc.Results The average operative time in PKRP group is a slightly longer than that in TURP group, but the difference was not statistically significant (P>0.05);Bleeding volume and operative complications occurrence were in PKRP group significantly lower than that in TURP group ( p<0.05);Intraoperative serum sodium and blood glucose values in TURP group compared with that of preoperative,the differences were statistically significant(all p<0.05),serum odium and blood glucose in PKRP group after surgery showed no significant change(P>0.05);Two groups postoperative 1 month of IPSS,RUV,Qmax,QOL compared with the preoperative value differences were statistically significant (all P< 0.01),but between the two groups postoperative 1 month compared these indicators values there were no statistically significant differences (all P>0.05).Conclusion PKRP,TURP are transurethral resection of benign prostate hyperplasia and effective surgical operative treatment at present,there are similar curative effect in improveing the symptoms of lower urinary tract obstruction。however, studies have shown that PKRP group is absence of TURP syndrome,postoperative complications reduced significantly,no significant change in serum sodium and blood glucose,bleeding volume is lower, PKRP is safer than TURP,is the ideal treatment of transurethral resection of BPH.But this study's sample sizes were small and long-term follow up not available,further studies that using larger sample sizes and randomized controlled trial are needed to confirm the conclusion. |