Contrast Research Of Intracranial Pressure, Cerebral Blood Flow And Electroencephalogram Between Pre-Cranioplasty And Post-Cranioplasty

Objective To investigate the effect of cranioplasty on Intracranial Pressure(ICP),Cerebral Blood Flow(CBF)and Electroencephalogram(EEG)and evaluate the relationship between cranioplasty and neurological recovery on patients with cranial defect.Methods Sixteen cases of patients with cranial defect were obtained before 2 days and 12 days after cranioplasty with noninvasive ICP testing analyzer in monitoring ICP value,transcranial doppler sonography(TCDS)in detecting CBF velocity parameters,noninvasive electroencephalograph in examining brain function changes and FIM scores in evaluating the neurological function.The patients'numerical results of the bilateral ICP values,the CBF velocity on the left,right internal carotid artery(ICA),anterior cerebral artery(ACA),middle cerebral artery(MCA)and posterior cerebral artery(PCA),the change of EEG and the neurologic evaluation before and after cranioplasty were statistically analysed by software SPSS13.0.Results Before cranioplasty,the ICP on the injured side lowered than the contralateral,the difference was statistically significant(P<0.05).After cranioplasty,there was no statistically significant difference between the bilateral ICP(P>0.05).Compared with the pre-cranioplasty,the ICP on the injured side increased after cranioplasty,which was significantly difference(P<0.05). The results of CBF measurement also indicated that the CBF velocity on the repaired increased (P<0.05).There was improvement in neurologic scores after cranioplasty,the difference was statistically significant(P<0.05).But there was not statistically significant difference between the change of EEG before and after cranioplasty(P>0.05). Conclusion Cranioplasty could significantly improve the intracranial pressure and cerebral blood flow on the injured side,which could be one of theoretical basis of neurological recovery,and it should be performed as earlier as possible.