Analysis And Curative Effect Evaluation Of Dysfunctional Dyspnea Dyspnea Syndrome In Patients With Functional Dyspepsia

Review:Postprandial distress syndrome symptoms of early satiation during meal intake, and postprandial fullness are inherently linked to meal ingestion.The Rome III consensus proposed to subdivide functional dyspepsia (FD) into two groups:meal-related dyspepsia or postprandial distress syndrome (PDS), and meal-unrelated dyspepsia or epigastric pain syndrome (EPS). The incidence of PDS was reported form 11.5% to 14.5% according to a systematic review. The complex and various pathogenesis has brought great difficulties to western medicine etiology diagnosis and treatment. However,The Chinese Medicine not only has a clear understanding of the pathogensis and the evolution law of PDS, but also has a remarkable curative effect according to the Yin and Yang and Five elements combining with the visceral manifestation theory.Objective:Through analyzing the clinical features of PDS and ancient literature, exploring the main pathogenesis and evolution law of PDS, this study aims to verify and evaluate the treatment of PDS by using Traditional Chinese Medicine.Research methods:We selected 30 cases which are in consistent with TCM diagnostic criteria of spleen deficiency-damp and qi stagnation syndrome, as well as western diagnostic criteria of postprandial distress syndrome(PDS). Make observation of the treating effect on main symptoms such as epigastric fullness after eating, early satiety, decreased food intake, belch, acid regurgitation and heart burning. Decoction was given 3 times a day half an hour after a meal,200ml each time. Patients were asked to avoid spicy food, thick and greasy food such as meat, milk, eggs, seafood, etc. Fill the observation tables before, during and after the treatment respectively. The effect of the treatment was valued by symptom score.Results:After 1,2 and 4 weeks of treatment, the general effective rates are respectively 30.00%,86.67% and 96.67%. The statistical analysis showed that there were significant differences among the effective rates after 1,2 and 4 weeks of the treatment. After 4 weeks of the treatment, the effective rates of fullness after eating is 100.00%, early satiety 96.67%, decreased food intake 96.43%, belch 100%, acid regurgitation and heart burning 100%. All the symptoms were significantly improved after 4 weeks’treatment.Conclusion:1. Spleen deficiency-damp and qi stagnation is one of the main pathogenesis of PDS.2. The treatment has achieved the desired result by grasping of the main pathogenesis, evolution law and using prescription to invigorate spleen, clear damp and promote the circulation of qi. The overall cure rate of the treatment has achieved 23.33%, the obvious effective rate was 56.67%, the effective rate was 96.67% and the ineffective rate was 3.33%.3. The effective rates for symptoms of epigastric fullness after eating, belch, acid regurgitation and heart burning were increased obviously in the early phase. The effective rates for early satiety and decreased food intake were improved progressively with extension of treatment course.