Study On The Correlation Between TCM Syndromes Of Nonalcoholic Steatohepatitis And Liver Function And Lipid

Objective To explore the relevance of TCM syndrome types of non-alcoholic steatohepatitis (NASH) and liver function and blood lipid index.Methods Choose 200 cases corresponding to diagnosis standards of NAFLD, including 28 cases of liver-depression and spleen-deficiency,42 cases of liver depression and qi stagnation, 63 cases of hot accumulate knot syndrome,49 cases of Phlegmy wet resistance syndrome and 18 cases of Phlegm accumulates with stagnant blood syndrome. Observe the change of the index of serum TBIL, DBIL, ALB, serum AST, ALT, GGT, the activity of ALP, FBG (fasting blood glucose), uric acid, serum triglycerides, TCH (total cholesterol), low density lipoprotein-cholesterol, high density lipoprotein cholesterol of these five groups of patients.Results 1. Syndrome of damp-group makes up the most distribution of non-alcoholic fatty liver syndrome, followed by the syndrome of phlegm-dampness resistance group.2. Non-alcoholic fatty liver disease is mainly concentrated in the age of 40-60. Compared with the damp group, liver stagnation and spleen deficiency, liver depression Qi stagnation, phlegm-damp resistance and phlegm and blood stasis has shown statistical significance (P<0.05). Male participants dominate the group of damp syndrome while females are the majority of the liver stagnation syndrome group.3. Liver stagnation, damp syndrome ALB content of internal resistance, phlegm syndrome of phlegm and blood stasis syndrome of phlegm group show a statistically significant difference (P<0.05).4.There is a significant difference between the groups of liver Qi stagnation and spleen deficiency and liver stagnation syndrome, syndrome of phlegm-dampness resistance and damp syndrome in the comparison of ALT activity (P<0.05). GGT activity difference between the syndrome of phlegm and blood stasis and phlegm group and the syndrome of phlegm-dampness resistance group is statistically significant (P<0.05). To compare the TG levels of liver-depression and spleen-deficiency syndrome, phlegm syndrome and damp syndrome, there is a significant difference between the groups (P<0.05).5.There is no difference between the five groups that compare levels of TBIL, DBIL, AST, ALP, FBG (fasting blood glucose), uric acid and LDL-C.6.TG level of liver stagnation and syndrome of phlegm-dampness resistance groups show sharp contrast with that of damp syndrome group.7. There is no significant difference among these five groups in terms of TBIL、DBIL、ALP、TC、LDL-C (P>0.05).8.HDL-C is at the normal level, and hence there is no statistics in this regard.Conclusion 1. Mainly concentrated in the age of 40-60, syndrome of damp-group makes up the most distribution of non-alcoholic steatohepatitis. Male participants dominate the group of damp syndrome while females are the majority of the liver stagnation syndrome group.3. Dysphagia with syndrome of intermingling of phlegm and static blood can be found in older age, and the dyndrome is very serious.4. The sharp decline of ALB can be an important indicator for diagnose dysphagia with syndrome of intermingling of phlegm and static blood. 5. The sharp increase of ALT can be an important indicator of syndrome of accumulated dampness-heat.