Study On The Correlation Between TCM Syndromes And Objective Index In Patients With Acute Myocardial Infarction

Purpose:Combined with objective indicators of the standard content of traditional medicine and modern medicine. To discuss the objective indexes between the internal relationship and external differences of Acute Myocardial Infarction in patients with different TCM syndrome type.To detect high-risk groups of patients with Acute Myocardial Infarction.To understand the objective index for the prognostic significance of different TCM syndromes of Acute Myocardial Infarction.So as to promote the Acute Myocardial Infarction study of TCM syndrome types of scientific and objective.To take effective measures as soon as possible to prevent and treat of Acute Myocardial Infarction. Provide scientific basis for clinical application and improve the treatment rate.Material and method:By reviewing 420 cases of Acute Myocardial Infarction patients records during March 2012 to November 2015, in the hospital of Liaoning University of traditional Chinese medicine.The records are sex, age, smoke, hypertension history, diabetes history, dyslipidemia, peripheral blood index, blood lipid index, cardiac muscle enzyme spectrum index and other clinical data.Reference to the Department of diagnostic and treatment norms, etc. The patients were divided into phlegm obstruction group, blood stasis group, Yin deficiency group, Yang deficiency group.The TCM syndrome types of patients with acute myocardial infarction were used as the dependent variables, and the objective indexes were used as the independent variables. To take statistical description, single factor analysis and multi factor analysis.Results:1.420 cases of Acute Myocardial Infarction patients with TCM syndrome type distribution: phlegm occlusion syndrome(accounted for 31.19%), blood stasis syndrome(accounted for 33.33%), Yin deficiency syndrome(accounted for 15.00%), Yang deficiency syndrome(accounted for 20.48%).2.Four groups of TCM syndromes in sex, age, smoke,hypertension history, diabetes history, dyslipidemia, white blood cell, neutrophil, triglyceride, total cholesterol, low density lipoprotein cholesterol, lactate dehydrogenase, creatine kinase MB, hydroxybutyrate dehydrogenase of chi square test, between group differences were statistically significant(P < 0.05).3.Four groups of TCM syndrome type in single factor analysis of variance of white blood cell, neutrophil, triglyceride, total cholesterol, low density lipoprotein cholesterol, lactate dehydrogenase, creatine kinase, creatine kinase MB, hydroxybutyrate dehydrogenase, differences between groups were statistical significance(P < 0.05).4.After multivariate analysis, found the phlegm obstruction syndrome of patients with AMI have relationship with age, smoke, total cholesterol, creatine kinase MB; Blood stasis syndrome of patients with AMI have relationship with hypertension history, diabetes history, white blood cell, total cholesterol, low density lipoprotein cholesterol; Yin deficiency syndrome of patients with AMI have relationship with age, hypertension, diabetes, dyslipidemia; Qi deficiency syndrome of patients with AMI have relationship with age, hypertension, total cholesterol, lactate dehydrogenase.Conclusion:1.In every TCM syndrome type of AMI, the proportion of four syndromes are in turn reduce one by one, blood stasis syndrome, phlegm occlusion syndrome, Yang deficiency syndrome, Yin deficiency syndrome.2.There is a correlation between the Acute Myocardial Infarction TCM syndrome type and white blood cell, neutrophil, triglyceride, total cholesterol, low density lipoprotein cholesterol, lactate dehydrogenase, creatine kinase, creatine kinase MB, hydroxybutyrate dehydrogenase. All of the factors can act as Acute Myocardial Infarction in TCM syndrome type of objective index basis.3.Age, smoke, hypertension history, diabetes history, dyslipidemia, white blood celtota, total cholesterol, low density lipoprotein cholesterol, lactate dehydrogenase, and creatine kinase MB had a certain predictive value for Acute Myocardial Infarction.