| Poultry industry is focus on growth and feed conversion rate (FCR) of chicken. As the main sugar transporter of chicken intestine, the expression of GLUT2and GLUT5are closely related to absorption of sugar, and influence on the utilization of feed. In this study, the transcription factor binding sites (TFBS) in1500bp upstream of GLUT2and GLUT5were detected for the single nucleotide polymorphism(SNP), which might have effects on FCR in chicken. Through aligning and analyzing transcription factor binding sites, one single SNP of GLUT2was found in TFBS and might influenced the recognition of transcription factor USF1. We used dCAPs technique for genotyping analysis with700samples and constructed the generalized linear mixed model for analyzing the effects of the SNP on growth traits and FCR. We found that all genotypes were within Hardy Weinberg equilibrium in the total group, but the genotypes in N301and N202groups were deviation from Hardy-Weinberg equilibrium. The effects of genotype on FCR is not significant (P>0.05). The effect of SNP of upstream of GLUT2on FCR is not significant. It could be a reference for future research on polymorphism of GLUT2and supply more information for gene mapping. |
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