Whole Genome Sequencing And Comparative Analysis Of The Genus Jiangella

The genus Jiangella is group of Gram-staining positive, aerobic actinomycetes with high G+C contents, which belongs to the family Jiangellaceae of the order Jiangellales in the class Actinobacteria. Strains of the genus Jiangella are widely distributed and well lived in natural environments. In this study, in order to explore the genetic variation and characteristic concerning the aspect of adaptation of these organisms in different niches, the draft genomes of Jiangella alkaliphila KCTC 19222T, Jiangella alba YIM 61503T and Jiangella muralis DSM 45357T were sequenced by using the next generation Hiseq 2000 sequencing platform in BGI Shengzhen, China. Where relevant, comparisons with another whole genome of type species of Jiangella gansuensis YIM 002T were also made. Genome sizes of four Jiangella genomes are from 5.59M to 7.66M, and their G+C contents are all close to 73%. Their genomes contain genes mainly involved in energy production and conversion, amino acid transport and metabolism, secondary metabolites biosynthesis, transport and catabolism, inorganic ion transport and metabolism, defense mechanisms, and so on. Based on the genome analysis of these four Jiangella species, we found that they had the powerful metabolic capacity to adapt well to the changing environments, and variety of transporter systems could enhance the strains ability to absorb nutrients. Futhermore, abundant gene clusters of secondary metabolite productions may improve the ability of competitiveness and defense of Jiangella strains to survive in special environments. These genetic characteristics of Jiangella spp make them better respond to the changing environment, and help them to have their unique role in nature.