Sangju Ganmao Tablets Production Process Improvement

Change the Sangju Ganmao tablets production process behind the and complex, theproduction process the status quo, improve labor productivity, improve product quality,improve the economic efficiency of enterprises, and for the Sangju Ganmao tablets of thegranulating process and coating process, the this article carried out experimental studyon.To roll WP50N/75dry Sangju Ganmao spray dry powder, granulator granulationtests on dry rolling suppress grain factors affecting the investigation and analysis, theresults showed that the roll pressure, roll speed and feed rate on three factorsdry pressedtablets greatest impact; orthogonal design method is preferred dry pressed grain processand investigate its dry granulation, the results show that the best dry pressed tabletsprocess: the roll pressure65bar roll speed12r/min feedspeed30kg/h, and the impact ofthe order of: roll pressure roll speed and feed rate; preparation of dry granulation processparameters optimized Sangju Ganmao tablets intermediate particles, and particle sizedistribution obtained particlesyield and grain moisture as the evaluation of intermediateparticles eligibility indicator of its quality evaluation.Granulation process improvements from the intermediate particles prepared SangjuGanmao plain film, and then analyze the target to the quality of the tablet, study SangjuGanmao plain film appearance, hardness, disintegration tablet weight difference,friabilitydegree, determination and stability of quality indicators to determine the qualityof the tablet core.Sangju Ganmao plain film by dry granulation process obtained Sangju Ganmaoparticles, the optimum parameters in accordance with the tablet, aqueous film coating byorthogonal design method, Sangju Ganmao plain film, to determine the best filmpackageclothing process parameters: coating liquid spray volume0.55kg/min of, theamount of coating liquid spray2-8r/min into the cylinder air temperature60°C.The final results of the study showed that: Sangju Ganmao tablets granulation andcoating process to improve quality has been significantly improved, reducing energyconsumption, energy savings, better economic and brand benefits to the enterprise,improve the enterprise’smarket competitiveness.