Study Of Electrochemical Sensor Based On Functionalized Carbon Nanotubes And Nanoparticles And Its Application

The thesis focused on preparation functionalized carbon nanotube sensors andit’s application. The main work is summarized as follows:1. In this chapter, thionine functionalized multi-walled carbon nanotubecomposite film (TH-MWCNTs) was prepared using EDC and NHS as thecross-linking agent. The morphology and structure of TH-MWCNTs werecharacterized by scanning electrochemical microscopy (SEM), ultraviolet-visibleSpectrophotometry (UV) and fourier transform infrared spectroscopy (FTIR). Then,electrochemical behaviors of hydroquinone, catechol and resorcinol were investigatedwith cyclic voltammetry (CV) and differential pulse voltammetry (DPV) atTH-MWCNTs modified electrode. CV and DPV results showed that theTH-MWCNTs modified electrode exhibited excellent recognition ability toward thethree isomers of dihydroxybenzene. Their oxidize peak currents were linear overranges from9.0×10-7to3.6×10-4mol/L for hydroquinone, from3.3×10-6to8.1×10-4mol/L for catechol and from4.3×10-6to9.0×10-4mol/L for resorcinol, with thedetection limits of2.7×10-7M,1.0×10-6mol/L and1.1×10-6mol/L, respectively. Theproposed method would potentially be applied to multi-component analysis inenvironmental control and chemical industry.2. Here a novel non-enzymatic glucose sensor was fabricated based onmulti-wall carbon nanotubes-chitosan/PVP coated nano nickel oxide modifiedelectrode (MWCNTs-CHIT/NiO-PVP/GCE). The morphology of composite wascharacterized by scanning electrochemical microscopy (SEM). The electrochemicalproperties of the sensor were investigated by cyclic voltammetry, amperometricmethod and electrochemical impedance. The results showed that the modifiedelectrode exhibited a high electrocatalytic activity for the oxidation of glucose．Underthe optimal conditions, the oxidation peak current had linear relationships withconcentration of glucose over the ranges of1.0×10-5~2.0×10-3mol/L, the detectionlimit was3×10-6mol/L. The proposed method was successfully applied in thedetection of glucose in serum．3. Based on the study of the first chapter, we fabricated an adenine biosensorbased on platinum nanoparticles electrochemical deposited on the thionine functionalize carbon nanotube materials. The influence of the volume of TH-CNT anddeposition time of platinum on adenine was investigated by cyclic voltammetry.Under the optimal conditions, a large number of platinum nanoparticles were loadedon the surface of TH-CNT and realized to detect the adenine. The oxidation peakcurrent had linear relationships with concentration of adenine over the ranges of1.0×10-6~1.0×10-4mol/L, and the detection limit was3×10-7mol/L.