| Among different types of chromatography, high performance liquid chromatography(HPLC) has been most widely used as an essential analysis tool for research, manufacturing, clinical tests and diagnostics. This is due to its universal applicability and remarkable assay precision. Covalent organic frameworks(COFs) are a class of materials consisting solely of the lighter elements in the periodic table. These materials have potential uses in areas such as storage, separation and catalysis.In recent years, core-shell silica microspheres have been widely investigated and used for highly efficient and fast separation with reasonably low pressure for separation.This paper studied the utilization of covalent triazine-based frameworks(CTFs) for extraction and concentration the trace pollutants in the environmental water samples as solid-phase extraction material.Moreover, the synthesis, characterization and chromatographic behavior of covalent triazine frameworks-coated silica microspheres stationary phase were systematically investigated.The specific details are as follows:1.The performance of CTFs by solid phase extraction were investigated for five polycyclic aromatic hydrocarbons(PAHs) in environmental water samples. Factors affecting the recovery of PAHs were investigated in detail, including the type and volume of eluent,volume of the sample,concentration of organic modifiers and elution time. Meanwhile, we established a method for the determination of five polycyclic aromatic hydrocarbons with HPLC-FLD,the detection limit was 0.5-1 ng/m L and the recoveries were in the range of 62.04%-96.10%.2.The study of the CTFs-coated silica microspheres packed column was demonstrated for the HPLC separation of phenol, benzophenone,phenetole, toluene,chlorobenzene,bromobenzene and iodobenzene with high selectivity and precision. Factors affecting the chromatographic behavior were investigated and discussed,such as the composition of mobile phase, the analyte mass, the column temperature and the flow rate.3.The chromatographic behaviors of CTFs-coated silica microspheres stationary phase were investigated by using more samples such as polycyclic aromatic hydrocarbons,phenols,aminobenzenes,nucleosides and so on.When compared to commercial C18, the results showed that the new stationary phase interact with solutes by hydrophobic as well as hydrogen bonding, π-π and inclusion effect et.al. |
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