Catechol Ligands Containing Molybdenum Complexes And Their Nanostructures Synthesis, Characterization And Anticancer Activity Study

The variety of different forms and sizes makes nanoscience a very rich field of research. Materials with different architectures and morphologies may have some novel physical and chemical properties. Ordered materials with nanoscale structures, which are generally synthesized through self-assembly between organic ligands and inorganic molecules, have attracted great attention due to their potential applications to catalysis, separations and nanodevices. Although there is an extensive literature on the synthesis and characterization of bulk inorganic-organic hybrid materials, few reports have appeared on their nanostructures.Molybdenum is an essential trace element that plays important roles in the global cycles of nitrate, sulfur, and phosphor. In this thesis, a series of metal-organic complexes with catechol ligand of molybdenum have been synthesized and characterized by IR,NMR,TEM,SEM,X-ray analyses. The main points are as follows:1 Four different complexes were synthesized by the reaction of tetra-butyl ammoniumβ-octamolybdate with catechol in the mixed solvent of CH3OH,CH3CN with NH₂CH₂CH₂NH₂, NH₂CH₂CHNH₂CH₃ added differently, and structurally characterized. (a) X-ray diffraction: The crystal structure results show that the nuclear anionic unit of the four complexes displayed the same coordination geometry but different crystal structure. (b) The nanostructure of these complexes were studied using microscopic technique. The nano morphologies of the complexes are determined by the crystal structures.2 Catechol was chosen to react with Na₂MoO₄ in the mixed solvent of CH₃OH,CH₃CN with NH₂CH₂CH₂CH₂NH₂, NH₃CH₂CH(NH₂)CH₃ added differently, and two different complexes were synthesized. The crystal structure results show that both of the complexes are connected to be a 2-D network by hydrogen bonds andπ-πinteractions.3 These molybdenum-based complexes show good anticancer activities. They show potential usage in the field of nanomedicine.