Electrospinning Preparation Of Biocompatible Nano-fibers

Electrospinning is a process that produces continuous polymer fibers with diameters in the range of nanometer to micrometer.Electrospun nanofibrous-mats,due to several useful properties such as high specific surface area,low diameter and high porosity,offer a versatile platform for a broad range of applications such as tissue engineering,sensor and fiber templates for the preparation of functional nanotubes.In this paper,several biocompatible blending nanofibers were prepared via electrospinning in order to improve spinnability and broaden their potential applications. The spinnability could be improved by adding other polymers.And the porous structure of PVP and sodium alginate non-woven nanofibers via electrospinning as well as their properties of biocompatibility and biodegradation would possibly be suitable for biomaterials.The spinnability,conductivity and fiber formation of blending solution were studied,and the fiber structure and properties were also primarily discussed in the paper. The results showed that the PVP concentration at 180g/L and spin voltage at 15kV were better for the formation of macro/nanofibers.Then PVP blending fibers were studied by electrospinning.The results showed that:the PVP/PVDF fibers obtained were better when using the concentration at 200g/L and the PVP:PVDF=6:4;PVP/PEO macro/nanofibers had better shape.The best shape macro/nano PVP/PEO blending fibers were obtained when using the concentration at 120g/L,the higher average molecular weight of PVP at 130×10⁴ and PVP:PEO at 8:2.Better nanofibers were obtained when the ratio of sodium alginate:PEO was 8:2.The anti-water property of the electrospun fibers has been improved by a combination of ethanol and CaCl₂(or CuAc₂)...