Genome-wide Analysis Of Cyclins In Popular And Maize

The study of plant cyclin family genes is one of the key subjects of plant genetics and molecular biology. The review paper mainly introduced the advances of cyclin family genes in the recent years including cell cycle process, cell cycle regulation, cyclin dependent kinase, cyclin dependent kinase inhibitor, cyclin. It also has a brief commentary of the prospect of plant cyclin family genes. However, Bioinformatics is across subject between computer science and biology, the primary content of which contains biological database and biological information analysis. The developments in nucleic acid database, protein database and the system of database integration were reviewed. Bioinformatics soft in some fields of plant cyclin family genes research was introduced, such as DNATOOLS, Clustal W/X, MAGA 3 and MEME. Cyclins are primary regulators of the activity of cyclin-dependent kinases (CDKs) and play crucial roles in cell cycle progression in eukaryotes. Although extensive studies have revealed the roles of some cyclins and the underlying mechanisms in plants, a relatively small number of cyclins have been functionally analyzed in maize.In this study, a full set of cyclin family candidate genes encoding cyclin_N domain in a complete genome of maize was identified and characterized by phylogenetic relationships, physical positions, conserved motif analysis and tandem or segmental duplications analysis, comparing with those in rice. The main results are summarized as follow:1. We identified 59 cyclins in the maize genome, all of the maize cyclins were grouped into A-, B-, D-, F-, SDS- and T-types by phylogenetic analysis, and the numbers of genes in those type were 11, 10, 21, 6, 4, and 7, respectively.2. In phylogenetic tree including maize and rice cyclin genes, six types (A-, B-, D-, F-, T- and SDS-types) were shared by both species, whereas rice had the H-, L-, and P-type cyclins that were not found in maize.3. We further found that the cyclin genes in the maize genome experienced a mass of tandem gene duplications on five chromosomes. However, no segmental duplications were found on maize chromosomes compared with rice.4. We identified 50 cyclins in the poplar genome, which were grouped into 7 types including A, B, C, D, T, J and Q types by phylogenetic analysis and the numbers of genes in those type were 9, 10, 2, 25, 2, 1 and 1 respectively.