Comparation Of Efficaies Of Three Kinds Of Positive Airway Pressure Treatment For Cheyne-stodes Respiration In Patients With Chronic Heart Failure

Objective To compare the efficacies for Cheyne-Stokes respiration in patients with chronic heart failure (CHF) by CPAP, BiPAP and adaptive servo-vrntilation (ASV) treatments.Methods Fourteen patients with CHF and CSR were recruited. During sleep, CPAP, BiPAP and ASV treatments were each performed for one night. Comparison before and after each treatment was made for the parameters of sleep respiration, sleep structure and quality.Results Compared with the baseline levels of apnea hypopnoea index (AHI), microarousal (MAI) and minimal pulse oxygen saturation (miniSpO2) before treatment, the apnoea hypopnoea index (AHI) and MAI were significantly decreased but miniSpO2 significantly increased following three kinds of treatment (all P<0.01). Comparison among three treatments showed that a) AHI and MAI was the lowest in ASV treatment but highest in CPAP treatment with a statistical difference among three treatments (all P<0.05); b) miniSpO2 was the highest in ASV treatment but lowest in CPAP treatment. Compared with the baseline sleep structure parameters, the percentages of StagesⅠ+Ⅱsleep/ total sleep time (TST) was significantly decreased but slow wave sleep/ TST significantly increases following three kinds of treatment (all P<0.01). Comparison among three treatments showed that a) StagesⅠ+Ⅱsleep/TST was the lowest in ASV treatment but highest in CPAP treatment with a statistical difference among three treatments (all P<0.05); b) slow wave sleep/ TST was the highest in ASV treatment but lowest in CPAP treatment with a statistical difference among three treatments (all P<0.05).Conclusion AHI, MAI, miniSpO2, sleep structure and quality could be all significantly improved in CHF patients with CSR by CPAP or BiPAP or ASV treatments. ASV demonstrated as the most effective therapy among three treatments.