The Diagnostic Value Of 320-slice Dynamic Volume Ct In Coronary Heart Disease

Objective1.To evaluate the accuracy in the diagnosis of coronary artery stenoses by 320-slice Dynamic Volume CT(DVCT) in contrast to selective coronary angiography(SCA).Methods320-slice Dynamic Volume CT angiography was performed in 86 patients(49 male,37 female) with established or suspected coronary artery disease(CAD) and the result was compared with that of selective coronary artery angiography(SCA). The rhythm of all the patients was stable sinus. Patients with initial heart rate>75bpm receivedβ-bloekers. All available coronary segments (≥1.5mm) were included in the evaluation. Lesions with>50% luminal narrowing were defined as significant stenoses. The accuracy was evaluated of 320-slice Dynamic Volume CT in detecting the stenosis of the variant branches or sengments of the coronary artery. According to the nature of motion artifacts and image evaluation for stenosis, image quality was rankedⅠ-Ⅳ.ResultsNone of the coronary segments (n=1032) needed to be excluded from analysis.SCA was used as the golden standard in evaluation, Overall sensitivity for classifying stenoses was 92.7%, specificity 96.1%%, positive predictive value 86.4%, and negative predictive value 98.0%.Aterial wall calcification was the main consideration influencing the accuracy of the assessment in coronary artery stenosis with 320-sliceDVCT scanner.Conclusions320-slice Dynamic Volume CT can satisfactorily reveal coronary arterial segment with the possibility as a potential, noninvasive method for excluding coronary heart disease.320-slice Dynamic Volume CT had high sensitivity and negative predictive value for detection of coronary significant stenosis, and will be a potential noninvasive method for diagnosing coronary artery disease.