| On the basis of T C M theory and the result of modern medical research, professor Wu GAOyuan pointed out that "Kidney-asthenia and liver depression, impairment of chong and ren channels" is the main pathogenesis of C S. And she acquired a good curative effect treated with acupuncture. According to this principle, we set up a treatment principle, that is "nourish the kidney and soothe the liver, invigorate Chong and Ren channels". We selected "Zusanli","Sanyinjiao","Guanyuan", "Taichong" as the prescription, used SD female rats of 11-15 months old as the natural climacterum models, to investigate the therapeutic mechanism of climacteric syndrome treated with electroacupuncture. After 30 days, we observed the change of serum E2 level, sexual stimulating hormone (FSH and LH), serum IL-2 and hypothalamic monoaminic neurotransmitter (NE, DA, 5-HT and 5-HIAA) of them. We also made the morphological observation of their ovary and suprarenal. The research indicated that electroacupuncture can evidently decrease the level of sexual stimulating hormone (p< 0.01-0.05) and elevate the level of serum E2 level of model rats (p<0.05); It can increase the content of serum IL-2 of model rats (p<0.05), it also can reduce the amount of 5-HT and 5-HIAA in the hypothalamus, which were increased in model group (p<0.05), elevate the amount of NE in the hypothalamus of acupuncture group (p<0.01); and decrease the ratio of 5-HT to NE nearly to the level of the youth group (p< 0.01). By means of research, we can draw a conclusion that eletroacupuncture can regulate reproduction endocrine and the function of vegetative nerve, it also can improve immunity of climacterum rats. It may produce a synthetic effect on nerve-endocrine-immune network of them, having the feature of totally regulating through multiway. |
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