| Objective:Magraine is one of the common and muiti-happaned diseases in neurologic medicine. It belongs to "Toufeng" , " headache" , " Jue headache" in Traditional Chinese Medicine(TCM).Following the fastening of the life rhythm and bursting of working space, the happaning rate and number of magraine is increasing continuously. It affects searlously the people's life quality and working efficiency. Nowdays there are many methods of curing magraine in the modem medicine and TCM , it is very important that it lowers the re-happaning rate of magraine and relieve the patients'pains.Now through observing the curative effect of Salvia Miltiorrhiza InjectionC SMI) and Ligusticum Chuanxiong Hort Injection ( LCHI) seing used in clinical therapy on Bianzheng Lunzhi, we will originally explore the therapeusis effect and mechanism of them on curing the magraine ,meanwhile investigate the feasibility of the TCM especially the injection of TCM which to be use:! in clinical therapy on Bianzheng Lunzhi.Methods:60 cases with magraine were divided randomly into tow groups ,the treatment group and control group. There are 30 cases and 30 cases in corresponding group. On the base of fundamental therapy ,30 cases (treatment group)were treated differently according to make the syndrome-sign clear. Those stagnation of Qi syndrome would be treated by I,CHI 160mg;and those stagnation of blood syndrome by SMI 30ml.30cases (control group)were treated randomly by any one of above tow injections without syndrome differentiation. They vere all treated once a day, 10 ~ 14 days as a therapeutic course , the time can't surpass 14 days. They were used in ivdrop with 5%GS or 10%GS or 0.9%Nacl 250ml.Tne symptoms and signs of two groups, the emorrheologic parameters and blood lipid of some in treatment group were observed before and after therapy.Results:1. The total effective rates of clinical symptoms ai-e90.00% and 80.00%in treatment group and control group respectively. The significant effective rates are 70.00% and 20.00%.There is significant difference between tow groups (P<0.01 ) .To the therapy effect treatment group is superior to oontroi group.2. The total effective rates of the TCM symptoms are 90.00% and 70.00%.The significant effective rates are 76.67% and 36.67%. There is significant difference between low groups ( P<0.01 ). T o the therapy effect treatment group is superior to control group.3. In all of the syndrome clinical symptom-signs and the TCM symptom-signs,there is significant difference before and after therapy iu two groups ( P<0.01 ), and thereis significant difference between the two groups after therapy ( P<0.05, P<0.01 ).4. In all symptom-complex the significant effective rate of the stagnation of Qi with stagnation of blood syndrome is higher than others ,and the stagnation of Qi with sputum-damp syndrome is lower.lt has no statistical difference in every syndrome (P>0.05).5. The emorrheologic parameters and blood lipid which were observed in treatment group had some improvements alter therapy. In the emorrheologic parameters, results there are significant differences before and after therapy except ESR( P<0.01 ),but the parameters of biood lipid have no significant changes( P>0.05 ).Conclusions:SMI and LCHF s curative effect on curing die magraine with Bianzheng Lunzhi is belter, especially on stagnation of Qi syndrome and stagnation of blood syndrome. They can relieve the clinical symptoms and symptoms of TCM of magraine patients. There are significant improvements on the parameters of emorrheologic except ESR, but the parameters of blood lipid have no significant changes.In all symptom-complex in TCM,to the significant effective rates, the stagnation of Qi with stagnation of blood syndrome is higher, and the stagnation of Qi with sputum-damp syndrome is lower,but there is no significant difference among those syndromes.The clinical curitive effect in treatment group is better than that in control group. |
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