Ge Lai Capsule Treatment Yin Heat Syndrome Type 2 Diabetes Phase ¢ó Study

Co. geli capsule is a new Chinese medicine. It is going along a clinic trail confirmed by SFDA. This essay would try to investigate and discuss the efficacy and safety of Co. geli capsule in treating type 2 diabetes mellitus diagnosed deficiency of Yin and excessive heat syndrome.Objective: To investigate the efficacy of Co. geli capsule in treating patientswith type 2 DM and to evaluate its safety.Methods: A randomized, double-blind, parallel-controlled trial was performed insixty-six patients with type 2 DM diagnosed deficiency of Yin and excessive heat syndrome. We chose Co. jiangtangshu capsule as the positive controlled drug. Among these patients, forty-nine patients were divided into the Co. geli capsule group and the other seventeen patients into control group randomly. Sixty-four patients finished the whole trail. All patients were treated for 8 weeks. The clinical symptoms were observed and the levels of blood glucose were tested every two weeks. The levels of HbA1c and serum lipid were tested both before and 8 weeks after starting the treatment to evaluate the efficacy of Co. geli capsule. The difference of the reductions of clinical symptoms, blood glucose, HbAic and serum lipid between the two groups before-and-after treatment were compared.Results: The results showed that Co. geli capsule could remarkably improve clinical symptoms and could obviously reduce the level of blood glucose, HbA1c, and cholesterol, which showed no statistical significance compared with control group.Conclusion: Co. geli capsule is a effective Chinese medicine in treating type 2 diabetes mellitus diagnosed deficiency of Yin and excessive heat syndrome. No adverse reaction is observed.