Acupuncture Combined With Experimental Osteoporosis In The Rat Insulin-like Growth Factor System

Objective:Osteoporosis sickness (Osteoporotic, O P) is suffers injury by the bone tissue microstructure, the bone ingredient and bone and so on the proportion unceasingly reduces, the bone qualitative change is thin, bone brittleness increase and easy bone fracture one kind of whole body metabolism barrier disease. Its disease incidence rate high, the illness complication is serious, becomes the serious human body health, the quality of life and even the life one kind of disease, therefore seeks one kind of security, the highly effective method of treatment, has become the hot spot which the medicine researcher pays attention. This topic take the experimental osteoporosis sickness big mouse as the research object, from the insulin type growth factor system adjustment angle, seeks the electricity needle to add the estrin treatment to the experimental osteoporosis sickness big mouse's treatment result and the function mechanism, osteoporosis take the time as clinical treatment sickness provides the powerful experimental basis.Methods:60 female Wistar rats, whose ages were all 5~6months and weight 210±10g, were tested ,then randomly devided into normal group , fake operation, ovariectomize control group , hormones group , electro-acupuncture group , electro-acupuncture in combination with hormones group, non-operation on 10 rats as a normal group, fake operation on 10 rats, the operation of castrating ovary on the rest of them, 10 rats in each group. In excises the ovary latter 5 days to observe the big mouse vagina to spread the piece to determine whether goes to the ovary to be successful, and gives anti- infection processing after the technique, the prevention infection. Raises for three months under the conventional condition. After three months in the anaesthesia situation, examines the big mouse's bone ore content and the bone density, firmly makes to order the mold to be successfulTest the BMC,BMD again after three months, the control group , hormones group , electro-acupuncture group, electro-acupuncture in combination with hormones group were conducted treatment after operation.all treatment were three-course.