Tune Intestine Soup Treatment Of Functional Constipation In Clinical Studies

Objietive:To investigate the efficacy of Tiaochangtang (TCT)in the treatment of chromnic functional constipation (CFC).Objective evaluate usefulness and safeties of TCT in the treatement of CFC,inquiry into its function mechanism .guide its in the clinical application. Methods:From march 2004 to march 2005, 60 patients with chronic functional constipation were enrolled in this study and divided randomly into two group. 30cases were received TCT as the study group, and 30 cases were received Liuweinengxiao as the control group. There were 60 patients in each group without significant in sex, age, symptom pattern between two group (P>0.05). Two groups have been received the medicine treatment for 4 weeks. The control group taking Liuweinengxiao third daily. The treatment group taking traditional Chinese herb of TCY twice daily. According to the observed results ,evaluated the treatment effectiveness. Security tests include the three routine exams ,kidney function (BUN ,Cr)and liver function (ALT).At last ,according to the treatment effect and the safe observation ,to evaluate the usefulness and the safety. Results:6 weeks later, we found the changes of two groups were better than before the treatment. The changes of clinic symptom and physical sign were significantly better after the treatment. The effective rate of the study group was 90% and the effective rate of the control group was 83.3%. But for the total efficiency, there were not difference between two groups(P>0.05). For the changes of clinic symptom and physical sign, the study group was significantly better than the control group(P<0.05). In the aspects of safety observing ,both groups have no the bad reaction. Conclusion:By four weeks treatment, the clinic effect of TCT is superior to LWNX in the aspects of sumptoms but the total effect of treatment is similar. Tiaochangtang was the significantly effective medicament for the functional constipation, especially for the cases with spleen qideficiency and stagnation slowly transferrd in the large intestines. It has been certified a safe and effective perscripyion of Chinese herbal medicine by clinic experiment .