Study On The Basic Data Of Mixed Constipation Patients And The Curative Effect Of Traditional Chinese Medicine On Nonclassical Constipation

Background:Functional constipation is a kind of functional gastrointestinal disorders. According to the guide of diagnosis and treatment of chronic constipation, it consists of four types:slow-transit constipation(STC), defecatory disorder(DD), mixed constipation(MIX), and notmal-transit constipation(NTC). The characteristics, quality of life, metal and psychological situation of mixed constipation is hard to find in the research before.And we found that there was a certain type of patients with main complaint of constipation and defecatory problems, but their faeces is not the typical constipation types. It is not dry, hard, ball-like, but oily with defecate difficulties.It is an untipical type of constipation.Objective:The aims of the reseach were:to get information of mixed constipation about clinical symptoms and psychological situation. To understand the symptom characteristics, mental status and quality of life. To compare the efficiency between traditional chinese medicine and the probiotics treatment in untipical constipation patients.Method:97 patinets diagnosed with functional constipation and 20 normal control subjects were recruited in the study. They were asked to fill in forms about constipation symptom, the SAS, the SDS, the PSQI and basic informations. The untipical constipation randomly divided into groups of probiotics treatment or traditional Chinese medicine. Fill out the review form after 4-weeks treatment. Analyze the symptoms changes and effective rate in groups.Results:(1) Of the 97 patients, the ratio of four types of constipation is 29.9%:13.4%:47.4%:9.3%(STC:DD:MIX:NTC). The MIX represented a fact of male to female ratio of 1:2.29, an average age of 48.2, an average suffering time of 11.6 years. Being women may contribute to mixed constipation, and aging too. (2)Mixed constipation patients’ short from health survey(36) showed their physiological function, body pain, general health, energy and social function had significant difference when compared with normal control group. PSQI showed their sleep quality and normal control group’s had significant difference. (3) In untipical constipation patients, both probiotics group and traditional Chinese medicine treatment group in symptom integral after the treatment has significant differences with symptom integral before. There was change in defecation frequency in TCM groups. When compared with each other, there was no significant difference in changes of symptom integral, defecate status, defecation frequencies. The effective rate had no differences in two groups.Conclusion:(1) A lot of FC patients were suffering from mixed constipation. It had a long time course and occured easily in women and people over 40 years old. (2) Mixed constipation patients had lower quality of life and sleep, and some merged with depression and anxiety.(3) For untipical constipation, Traditional Chinese medicine treatment is valid and efficient.