Pharmaceutical Research Gastritis Rather Dispersible Tablets

The weiyanning dispersible tablets are modern compound Chinese medicine that studied by changing form of prepared drugs that used in clinic— Weiyanning powder, which is used to cure chronic gastritis and peptic ulcer diseases. According to the standard of the Chinese new drugs, we studied its preparation process, quality standard and preliminary stability systematically with modern science and technology. The study details are as the following:1.Study on Literature: With the guidance of Traditional Chinese Medicine, the source of the prescription, the survey of the studies and the significance of developing the issue are elaborated widely. At the same time, we sum up the present research about dispersible tablets of Traditional Chinese Medicine.2.Study on preparation process: With the getting rate of volatile oil and the immerse amount of cream, by orthogonal design.we get the optimal extraction methord of the prescription. With the index of the disintegration time, palate, the level of disintegration and the productive maneuverability, and so on, the tablet forming technology was studied with parallel-contrast and orthogonal experiment. We select disintegration, filler, flavor enhancer, sorbent, lubricant and flow aid. We choose the preparation progress.The optimal proportion of M, P and pressure guarantees the time and level of disintegration, the optimal proportion of Glidant and Lubricant guarantees the productive maneuverability. We also progressed the middle test production study and validated the preparation process.3.study on quality control method: Establish the examination items of the preparation general rules of Weiyanning dispersible tablets with recommend the disintegration time, palate,dissolution, the level of disintegration and other indications. Set up the composition identified method of Citrus medica L and Citrus medica L.var.