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Hubei Of Ophiopogon Chemical Composition And The Pieces Quality Standards

Posted on:2007-11-18Degree:MasterType:Thesis
Country:ChinaCandidate:W S YangFull Text:PDF
GTID:2204360185951769Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
Liriope spicata var. prolifera Y. T.Ma belongs to genus Lirope plants of liliaceae. It is a traditional Chinese medicine that can nourish yin and promoting the production of body fluid, moistening the lung to arrest cough. It can cure cough due to dryness of the lung, cough due to consumption, insomnia, perturbed, astriction etc. Since 1960s, interal and external scholars have made many researches on pharmacognosy, phytochemisty, pharmacology and clinical treatment of Liriope spicata var. prolifera Y.T.Ma.Modern clinic and pharmacologic researches found that the components of saponin come from Lirope can improve myocardial contractive, protect myocardial cell, anti-arrhythmia and improve the mouse' s ability of endure hypoxia. In addition, The Liriope injection have effection on anti-cancer and declining the blood-sugar.With solvent and chromatographic methods to extract and isolate the effective composition, we get aether, ethyl acetate and n butanol part. Then we adopt chromatographic methods to isolate ethyl acetate part, and get four compounds from it and identificate them as β-sitosterol, daucosterol, oleanolic acid and 25 (S)-ruscogenin 1-β-D-fucopyranoside-3-α-L-rhamnopyanoside by the physical, chemical and IR, 1H-NMR, 13C-NMR, MS spectrum.Concerning the researches on quanlity standards for the herbal pieces, the pharmacopoeia regulated that Ophiopogon's p a ozh i is "wash clearly, smooth deeply, stave and dry. " ,Lirope's paozhi is "remove trash , wash and dry." This thesies established the quanlity of the five herb pieces. Including character, distinguish, moisture,qualitative analysis of saponin by TLC, content of saponin by UV. It provides scientific reference for Liriope's reasoned paozh i approach and application.This paper summarizes the research survey of Fagopyrum plants from consititution, pharmacological action and so on. It provides some value for Exploitation and utilization.
Keywords/Search Tags:Liriope spicata var. prolifera Y. T. Ma, Isolation, Identification, Quality standard
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