Rheumatoid ¢ñ Prescription And Sulfasalazine Treatment Of 80 Cases Of Ankylosing Spondylitis In Clinical Research

Ankylosing spondylitis (AS) is a systemic disease with chieflychronic inflammatory of axis joints and insertion including muscle tendon,ligament and bone. Its characters are inflammatory waist pain, muscletendon inflammation, peri-arthritis and manifestation out of joints. ASmainly attacks sacroiliac joints, spine and limb joints. It results incalcification of joints and tissues, ligaments, inter-vertebral discsaround joints. At last it will become bony ankylosis. At present, AS'etiological factor isn't clear. It results in absence of aiming treatmentand unsatisfactory in effect. Since two years ago, with the guidance ofmy tutor, professor Yang, I use "No 1. Rheumatism" recipe and SASP totreat 80 AS patients, which professor Yang summaries on the basis of manyyears clinic experience. Clinical research makes clear that this recipehas satisfactory effct in curing AS patients. We analyzed the clinicaldata and generalized that "kidney is deficient, cold and damp block themeridians" is the main TCM (Traditional Chinese Medicine) etiologicfactor andpathogenesis. "Reinforcing the kidney and Dissolving dampness,Dredging collaterals and Resolving pain" is the basic curing way.AS is amodern medicinal name. It belongs to blockage syndrome of TCM.There are not clear records of AS in TCM ancient medicinal books. But manydescriptions about "kidney blockage", "bone blockage","intractableblockage", "acute arthritis", "waist pain" are resemble to AS in pastdynasties medicinal books. These literatures provide very important tutorsignificance to our treatment in AS. Modern TCM scholar process a greatdeal of helpful research work on AS' pathogens and mechanism, diagnosisand treatment based on an overall analysis of the illness and the patient'scondition. But present researches are absent of consolidated understandand standard. It takes many oppugns and challenges to the validity andsecurity of TCN diagnosis and treatment. It goes against development instandardization and reliability of differentiation of syndromes. The clinical study aimed at evaluating the curative effect of" No1. Rheumatism" recipe. We established a relatively objective effectassessing method on the basis of international rather versatile effectassessing criterion. Our aim was to promote the transformation fromexperience medicine to evidence-based medicine (EBM).After treatment of 80 AS patients' symptoms, physical signs andlaboratory indexes were ameliorated very well. Analysis of this recipe'curative effect show: This recipe's clinical remission rate was 10.0%.Apparent available rate was 20.0%. Available rate was 50.0%.Invalid rateis 20.0%. General available rate was 80.0%. These prove that" No 1.Rheumatism" recipe has satisfying curative effect to AS patients.In general,"No 1. Rheumatism" recipe can better improve clinicalsyndrome,physical sign and laboratory examination of AS patients. Theresults are satisfactory for both patients and us. It also needs furtherresearches in future.