Strain Rate Imaging Evaluation Of Atrial Septal Defect Before And After Occlusion Of The Right Ventricular Long Axis Function Changes

Objection To assess the change of the right ventricular long-axis function before and after transcatheter closure of atrial septal defect (ASD) by Strain rate imaging ,and to discuss its clinical value. Methods fifty patients [aged 25 (7-65) years] with isolated atrial septal defect of the secondum type before 3 day and 1 week and three month after Amplatzer Septal Occluder closure and 50 healthy controls [aged 22.5 (2-60) years ] were studied .Atrial and Ventricular strain rate curves were assessed in the middle of their corresponding lateral walls in an apical four-chamber view. The systolic,early diastolic, and late diastolic strain rates peaks were measured. Results Compared to healty volunteera , patients with isolated atrial septal defect risesd signijicantly the right ventricular systolic ,early diastolic, late diastolic in strain rate (P<0.05).Compared to before atrial septal defect closure, patients 1 week after atrial septal defect closure, decreased signijicantly the right ventricular systolic ,early diastolic, late diastolic in strain rate (P<0.05). Compared to 1 week after atrial septal defect closure, patients 3 month after atrial septal defect closure, decreased furtherly the middle of ventricular septal systolic ,early diastolic, late diastolic in strain rate (P <0.05 )Conclusion right ventricular long axis function significantly increased in patients with ASD. Followed by the increase of PASP, the right ventricular long-axis function decreased gradually. Due to ventricular interaction, left ventricular diastolic filling pattern was effected. After, right ventricular long-axis function significantly improved.