Diabetic Macular Edema Type Analysis, And Related Factors

ObjectiveTo explore the relationship between the classification of diabetic macular edema (DME) and the patient's age, diabetes duration, visual impairment, diabetic retinopathy (DRP) and some degree of blood test results, etc., with a view to provide relevant basis for the early treatment of DME , to reduce its incidence, lower visual impairment have important significant.MethodsRetrospective analysis into line with the standards of 62 cases DRP patients (97 eyes) of the hospitalized cases from January 2005 to August 2007 in Chengdu University of Traditional Chinese Medicine Hospital Eye hospital, records of patient's age, vision, diabetes duration, and a part of blood test and the results of fundus fluorescence angiography (FFA) results to determine DRP staging and DME type. All data use SPSS13.0 software to statistical analysis and processing.Results1. In the 62 cases (97 eyes) of DRP, there is 22 eyes (22.7%, 22/97) of the limitations DME, 33 eyes (34.0%, 33/97) of diffuse diabetic macular edema, cystoid edema (DDME), 42 eyes (43.3%, 42/97) of cystoid macular edema(CME) (including simple cystoid macular edema and cystoid macular edema and diffuse macular edema).2. Between the three tape of DME, visual impairment of the patients of DDME, CME is more serious than the limitations DME, and their differences have statistically significant (p <0.05); with the aggravation of DRP, the degree of diabetic macular edema have increasing trend, the DRP condition of DDME is more serious than the limitations DME, and their differences have statistically significant (p <0.05); the urea (BUN) and uric acid (UA) levels in patients of CME is higher than DDME, and their differences have statistically significant (p <0.05); the mean corpuscular hemoglobin (MCH) levels in patients of limitations DME is higher than CME. and their differences have statistically significant (p <0.05).3. Between the three tape of DME, the history of diabetes, creatinine (Cr), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL - C). lipoprotein (a) (LP (a)), fasting blood glucose levels ,hemoglobin (Hb), hematocrit (MCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC) in patients, their differences have not statistically significant (p> 0.05).Conclusion1. DME is one of the important causes which cause the visual impairment of DRP, the visual impairment of DDME, CME is more serious than the limitations DME.2. The occurrence and severity of DME have some relevance with the severity of the DRP, the DRP condition of DDME and CME is more serious than the limitations DME. But these is not strictly identical corresponding relations between DME occurred in the timing and the staging of DRP .3. In the progress of DME, BUN and UA will increase with the severity of the DME ,they may be an important factor of DME in the process of developing .4. The Fasting blood glucose levels in patients is no significant difference with the three types of DME ; hemoglobin may be a factor to affect the degree of DME.