Radish Seed Of Total Alkaloids On High-fat Diet In Apoe Knockout Mice Lipid Effects Of Nos Experimental Study

Purpose: Discussion Radish Seed total alkaloids of high-fat diet ApoE-knockout mice lipids, NOS Experimental StudyMethod: Optional 13-week-old male ApoE-knockout mice 75, elect their peers of the same sex C57BL/6J mice were 15, with electronic weighing scale and record the weight of the mice, the Apoe gene defect in mice under the 75 weight from small to big label, the use of random number table is divided into five groups, each with 15 rats per cage 5. Normal diet fed group: C57BL/6J mice, 15 for the blank control group. S & P food group fed normal rat feed, high-fat group of mice fed high-fat high-sugar feed, delivery 8 weeks, 8 weeks after feeding in fasted animals after eating the Last 12h, weighed, picking eye animals were sacrificed after blood sampling , preparation and measurement of plasma and serum after execution,Kit instructions by using radioimmunoassay triglycerides, total cholesterol, high density lipoprotein cholesterol, measurement of NOS activity in serum.Result: Feigan diet for 8 weeks, total cholesterol, triglyceride, low-density lipoprotein increased significantly lower high-density lipoprotein, NOS activity declined.Conclusion: Through the ApoE gene knockout (Congenital anomalies, internal), and Feigan diet-induced (acquired intervention, external) factors that lead to a double multi-layer composite of atherosclerosis(as) and serum triglycerides NOS for research on the impact of the successive days of dual-factor authentication interference than the single factor interventions led to more pronounced degree of hyperlipidemia.