Refreshing Capsule Technology And Quality Standards

Purpose: Yishen Capsule is the experience of clinical capsule. To alleviate chronic fatigue syndrome have a very significant effect. It is very popular with the majority of patients welcome. But the preparation process and quality standards is currently empty. To ensure the effectiveness of clinical and the stability of the quality of the production process, our production process and its quality standards of the exploration. Pharmacological experiments and by the guidance of scientific methodology to seek a more scientific method, the greatest degree of balance between the two.Method:①Through pharmacological experiments to compare the deficiency treated group and control group differences, son of the leek to conduct a quantitative evaluation of Pharmacological Action.②To L9 (34) orthogonal experiment, to leek son percentage of the extract to determine the best extraction technology of Semen Allii Tuberosi. Radix Ginseng, Radix Puerariae, Schisandra chinensis(Turcz.)Baill, with Ginsenoside's determination as a preferred extraction. Yishen capsules molding process is its heap density, repose angle, moisture three index comprehensive assessed. Elected by this method is more scientific, more rational preparation process. Ginseng, Radix Ginseng, Radix Puerariae, Schisandra chinensis(Turcz.)Baill's quality standards have been studied. With the TLC method used to identify and with the HPLC method used to determination.③quality standards of the study, On ginseng, Schisandra with Gen and TLC method for qualitative identification, Ginseng, puerarin HPLC method used to determine the content.Result: Water extract of Semen Allii Tuberosi activity of strong by pharmacological. It's the best extraction process 10 times to increase the amount of water, extraction time of 1 hour, extraction times of 2 times. Radix Puerariae, Schisandra chinensis(Turcz.)Baill's the best extraction process is 6 times of 70% ethanol, extraction time is 1 hour, extraction times of 2 times. On ginseng, Schisandra with Gen and TLC method for qualitative identification, Ginseng, puerarin HPLC method used to determine the content.The methods are Schisandra the identification and determination.Conclusion: Preparation process is reasonably practicable, the quality control...