Mcm-41 Load Aromatic Oxime Palladium Catalyst Preparation And Catalytic Suzuki Aryl Coupling Reaction

Suzuki coupling reaction which aryl halogenated react with phenyl boronic acid is an important method to construct biphenyl unit, has been used to prepare the light-emitting materials, drug synthesis and other aspects. Although homogeneous catalysts have high activity in Suzuki coupling reaction, but it is very difficult to recovery or recycles after the reaction over, at the same time, product may be contaminated from catalyst .So, preparing highly active, reusable and immobilized palladium catalyst is mainly topic in Suzuki coupling reaction.MCM-41 loading 4-hydroxyacetophonene oxime cyclopalladium catalyst is prepared by the method of modifying MCM-41 surface with KH560 reagent. The catalysts are characterized by Thermo gravimetric Analysis (TG), Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscope (SEM), N₂ Absorp- tion (BET), inductively coupled plasma Atomic Emission Spectrometry (AES-ICP). These analysis methods shows that the synthesized MCM-41 covering oxime ligand cyclopalladium catalyst is joined chemical grafting immobilization into the surface of MCM-41, while retaining some of the molecular sieve pore structure characteristics, at same time, the prepared catalyst had been measured the amount of palladium.For studying the catalysts activity, different subsistent aryl halogenated are selected as the substrate with phenylboronic acid in Suzuki coupling reaction. The effects of solvents, bases and the amount of catalyst are tested as the mainly parameters. For the MCM-41 loading 4-hydroxyacetophonene oxime cyclopalladium catalyst, Suzuki coupling reaction condition were optimized to determine the most appropriate reaction system, the results shows that K₂CO₃ is the most appropriate base,ethanol-H₂O(5:1) is the most appropriate solvent and 40℃is the most appropriate temperature.