Cardial Abnormal Diagnosis By Echocardio-graphy In CKD Patients And Risk Factors Exploring

Objective:To explore cardial abnormal diagnosis by echocardiography in patients with chronic kidney disease(CKD) and risk factors. Methods:The medical records and associated data of 210 inpatent cases at 40-75 years old with CKD2-5 stage,which came from November of 2009 to June of 2010,were analyzed retrospectively by SPSS17.0 Results:(1) The detection rate of diastolic dysfunction was significantly higher than systolic dysfunction (P=0.000); The detection rate of left atrial enlargement was significantly higher than that of left ventricular enlargement (P=0.000); The detection rate of interventricular septum thickening(IVST) was significantly higher than that of left ventricular posterior wall thickening(LVPWT) (P=0.000); LVH accidence (according to LVH index) was significantly higher than IVST detection rate (p=0.001), LVH in females had significantly difference than that in male (P=0.000). However, if applying a different diagnostic criterion for LVH of 2007 European hypertension guideline, no significant differences (p=0.068). (2) The systolic blood pressure(SBP), pulse pressure(PP), serum creatinine(Scr) in IVST group were higher than those in non-IVST. The serum phosphate in LVPWT group in addition to the above factors was also higher than that in non-LVPWT group, but in subgroup analysis of CKD5,only the SBP compared with the control group was significantly different.In LVH group SBP, PP were higher than that in non-LVH group, and hemoglobin(Hb), body mass index(BMI) were lower than the control group. Logistic regression analysis indicated that only anemia, BMI were statistically significant. Conclusion:(1) The highest positive rate of cardial abnormal by echocardiography in patients with CKD is from LVH by the formula. The diagnostic criterion of 2007 European hypertension guideline may be better than the one extensively applied presently. (2) 40-75 years CKD patients, SBP, PP, anemia, BMI, female are likely to be risk factors for LVH, but anemia,BMI may be more significant risk factors.