| Objective:Pass the observation keeps blood by benefit gas and cultivates mental calm the Chinese herbal medicine compound prescribe of tranquilizing the nerves the law composition to cultivate mental calm the grain dyes an easy Sun spot vs the P53 gene revolution mass domestic rabbit pattern the blood plasma is huge the impact of the contents for biting cell to rove around t o repress factor(MIF), inquire into its possible action machining, provide for the clinical application obj ective basisMethod:Takes 18 male domestic rabbit, unifies the high fat diet by the ball pouch disposable damage domestic rabbit arteria carotis communis anterior to feed for 8 weeks,8 week terminal row colored Doppler excess birth examination, the domestic rabbit which forms the arteria carotis communis anterior gruel type mottling divides into stochastically the model control group, a spiritual cultivation friability, and Xin cuts down his sandbank group, each group of 6, and give the wild p53 gene extension to dye, in addition takes 6 for the blank control group. Give medicine to infuse stomach for 2 cycles and carry on medicine triggering during 10 weekends.The Mao allied immunity adsorbs a law to examine each domestic rabbit blood plasma huge bite cell to rove around the horizontal of repressing the factor(MIF).Result:MIF measureses result enunciation:Compared with the control group, each group in the 8 weeks increased the content of MIF P<0.01 was statistically significant; 10 weeks compared with the 8 week MIF decreased P<0.01 was statistically significant; 10 weekend Yang Xin particle group and the simvastatin group than in the P<0.01 significant difference. Yang Xin particles can reduce the p53 gene transfection in rabbit plasma vulnerable plaque macrophage.Conclusion:yangxinkeli group may be by reducing the p53 gene in plasma rabbit model of vulnerable plaque macrophage migration inhibitory... |
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