The Influence And Preventing Countermeasures Of Peptic Ulcer And Upper Gastrointestinal Bleeding Under Sudden Changes In Temperature (Low Temperature) Of Nanchang

Objective:Research influence of method of different intervention to peptic ulcer and upper gastrointestinal bleeding under sudden changes in temperature (low temperature)of Nanchang, selected the best intervention model to prevent peptic ulcer and upper gastrointestinal bleeding, formulate peptic ulcer and upper gastrointestinal bleeding prevention strategies in colder climates.Methods:The cases patients (aged>18,<70) of hospital or clinic under gastro scope inspection found activity stomach or/and duodenal ulcer during January of 2008 to January 2010. They were randomized, when cold wave arrived for the corresponding season intervention; observe the bleeding, abdominal pain, indigestion conditions, Inspection of helicobacter pylori and gastro scope review at winter end. All data using SPSS17.0 package processing, Statistics analysis is used forχ2 inspection, and P<0.05 is greup.Results:Into groups of patients 169 cases, lost to 16 people, follow-up 481 person-times, the group of health education 111 person-time, the group of Ranitidine 122 person-time, the group of Rabeprazole 131 person-time, the group of control 120 person-time, During follow-up, people without hematemesis occurred during follow-up black then. The group of health education appear abdominal pain person-time is 21, the rate of abdominal is 19.91%; the group of Ranitidine appear abdominal pain person-time is 17, the rate of abdominal is 13.93%; the group of Rabeprazole appear abdominal pain person-time is 28, the rate of abdominal is 21.37%; the group of control appear abdominal pain person-time is 51, the rate of abdominal is 42.50%. The rate of abdominal for the group of control is highest in four groups, P< 0.05 compared with other groups, there are significant differences. The rate of dyspepsia symptoms (belch, anti acid, full bilge) for the group of control is highest in four groups, P< 0.05 compared with other groups, there are significant differences too. The rate of gastric ulcer with gastro scope inspection for the group of control is highest in four groups, P<0.05 compared with other groups, there are significant differences too. The rates of helicobacter pylori infection for patients into groups is 59.26%, The rates of helicobacter pylori infection(84.62%)for patients who peptic ulcer relapses than not relapses (40.93%) is significantly higher, P< 0.05, there are significant differences.Conclusion:(1) Health education for patients with peptic ulcer can effectively prevent and reduce the cold climate of ulcer recurrence, and reduce the complications of upper gastrointestinal bleeding. (2) However, H2 blocker or add services proton pump inhibitors and other acid-suppressing agents can not prevent or reduce the recurrence of ulcer disease and upper gastrointestinal blood. (3) In cold climates, peptic ulcer Helicobacter pylori infection is still the main pathogenic factors and one of the main factors of recurrence.