Clinical Observation Of Xingnaojing Timing Treatment Of Massive Cerebral Infarction

Objective:Observeing the clinical efficacy of Xingnaojing timing treatment of massive cerebral infarction, in order to provide a new treatment methods and ideas for the treatment of the disease.Methods:The 75 patients were randomly selected into the timing treatment group with 30 cases,the not timing treatment group with 30 cases and control group with 15 cases. Control group was treated with dehydration, reducing intracranial pressure, improving circulation,protecting brain cells and other routine western medicine treatment. The timing treatment group intravenous drip 0.9% sodium chloride solution 250ml with 20ml Xingnaojing at 7-9 am daily. The treatment of not timing treatment group were in the same with the timing treatment group except to choose other time. Three groups were treated for 15d. The patients would conduct neurologic impairment score and non-invasive monitoring of cerebral edema respectively before treatment and after treatment of 5d, 10d,15d. At the same time, the patients would carry out Chinese symptoms score and observe the clinical efficacy. In addition,we would monitor the routine examination of blood,urine and stool, liver and kidney function, blood pressure, electrocardiogram, blood clotting function and observed the adverse reactions in order to assess the safety of drugs. Results:15d of treatment, clinical efficacy and efficacy assessment of traditional Chinese medicine have shown that the efficacy of the timing treatment group was significantly better than the other two groups(p<0.05). Activities of daily living status and symptom score of traditional Chinese medicine have shown that the efficacy of the timing treatment group was better than the not timing treatment group and the not timing treatment group was better than the control group (p<0.05).In neurological deficit score, only the timing treatment group had statistically significant after treatment for 5d and the treatment of three groups was effective after treatment for 10d; After treatment for 15d, it show that the efficacy of the timing treatment group was better than the not timing treatment group and the not timing treatment group was better than the control group. In monitoring of cerebral edema disturbance factor, after treatment for 5d, the affected side of treatment group compared with the control group,only the the timing treatment group were effective(p<0.05); After treatment for 10d, it show that the efficacy of the timing treatment group was better than the not timing treatment group and the not timing treatment group was better than the control group;After treatment for 15d, it show that the treatment of three groups are effective and the timing treatment group had the optimal efficacy. There were two cases of abnormal liver function in the not timing treatment group,but no adnormal change in other groups.Conclusion: The clinical efficacy of Xingnaojing combined western medicine treating massive cerebral infarction was significantly superior to conventional western medicine. Combine time therapy, it could more effective reduce brain edema,promote the recovery of neurological function, improve clinical symptoms, enhance activities of daily living and provide a new treatment ideas for the treatment of stroke in Chinese medicine.