The Analysis Of The Disease Constituent Ratio In 1130 Inpatients Of The Department Of Nephrology

Objective: To analyzing the disease constituent ratio and prevalent condition of 1130 inpatients in the department of nephrology and to discover the characteristic of age predilection and sex predilection of different diseases. The results reflect the condition the primary renal disease and medical treatment, and finally provide scientific basis for prevention and curing of disease.Methods: In order to understand the feature and epidemiological characteristics of disease of patients in the department of nephrology in the second affiliated hospital of Dalian medical university, we investigated and analyzed retrospectively the clinical records of the patients of the department of nephrology of the hospital from July, 2009 to June, 2010, we also tackled, classified and had the statistical analysis of the data.Results:1. Etiology constitution: diabetic nephropathy(31.39%) is the main cause of chronic kidney disease. Secondly, glomerulonephritis (28.24%), nephropathy with begin essential hypertension (15.57%), reason unknown (9.76%), chronic interstitial nephritis (3.62%), polycystic kidney disease(4.46%), obstructive nephropathy (0.84%), lupus nephritis (1.76%), multiple myeloma kidney disease (0.42%), ANCA-associated vasculitis (0.10%), drying syndrome renal impairment (0.10%), chronic pyelonephritis (0.31%), leukemic renal impairment (0.31%), Henoch-Schonlein purpura glomerulonephritis (0.73%), hyperuricemic renal impairment (0.21%), hepatitis B virus associated glomerulonephriris (1.76%), autoimmune correlation renal impairment (0.42%). the main causes of acute renal failure injury was pre-renal, simple urinary tract infections is the most common. Also, the study indicated that diabetic patients were susceptible to urinary tract infection.2. The pathological results of renal biopsy from 91 cases revealed that Mesangial proliferative glomerulonephritis and membranous nephropathy were the most common disease in renal disease, respectively accounting for 57.14% and 25.27%. Secondly, focal segmental glomerulosclerosis (5.49%), Membrano proliferative glomerulonephritis (4.40%), crescentic glomerulo- nephrits(3.30%), segmental glomerulonephritis (2.20%) and minimal- change disease (2.20%).3. Distributional of age and sex: Of the all 1130 inpatients in the department, 516 were male, and 614 were female, male to female ratio was1:1.19. Meanwhile the hospitalized patients is classified by aged (less than20, 20-29, 30-39, 40-49, 50-59, 60-69, 70 to 79, 80-89 classification). The prevalence rate of inpatients of the department of nephrology has two peak: 70 to 79 years old (20.5%), 60 to 69 years old (18.3%), and secondly hospitalized patients for 50-59 (17.0%), 40 to 49 years old (14.0%). A high incidence rate of chronic kidney disease occurred at the age from 60 to 80 years. Diseases of the glomerulus had two peaks (20-30 and 40-50 years); Acute renal failure to 14-20 and 60 to 80 year old for peak; It is high incidence in urinary tract infection at the age of 70 to 80.4. Death: The main cause of death of 26 patients in the department of nephrology were severe infection and multiple organ failure (42.32%), cardiogenic shock (23.08%), uremic encephalopathy (23.08%), acute renal failure (3.84%), pulmonary embolism (3.84%), cerebral embolism (3.84%).Conclusions:1. Primary glomerulonephritis, diabetic nephropathy and nephropathy with essential hypertension were the main pathogenies of inpatients with chronic kidney disease.2. Gender and Age Distributions: Women were more than men, the age pee- k of incidence was among 70-80 years old, and getting older.3. The patients with Mesangial proliferative glomerulonephritis and the membranous nephropathy among the glomerulonephritis were the most common.4. The number of inpatients chronic kidney disease 5 in the department of nephrology was the highest.