C-reactive Protein For ERCP Postoperative Pancreatitis Monitoring And Evaluation Of Clinical Application Research

Purpose:Along with the development of the Endoscopic equipment and the improvement of operation, the Endoscopic retrograde hinders imaging (Endoscopic retrograde cholangiopancreatograph,ERCP) each operation become more convenient, but also cannot ignore the postoperative complications, the early postoperative pancreatitis ERCP main complications, bleeding, perforation and biliary infections. Now to do that the induced ERCP acute pancreatitis is ERCP and EST postoperative a serious complications, is also the most see complications after ERCP, accounted for more than50%of the postoperative complications. Have reported in the literature to the incidence of postoperative ERCP acute pancreatitis is2%-40%. This study is to investigate the c-reactive protein ERCP postoperative pancreatitis to the early diagnosis of pancreatitis and the severity of the prediction and evaluation.Clinical data and methods:To make strict into and exclusion standard, choose December2010to December2011in kunming, The Second Affiliated Hospital Medical College hospital treatment, by bultrasonography, CT or MRI (MRCP) confirmed the bile duct for42patients, male18cases (42.9%), women24patients (57.1%), sex ratio1:1.33. And, at the age of45-72year old group, the average age is67years old. Will execute ERCP, to Endoscopic incision nipple sphincter (Endoscopi-c sphincteroto-papillotomy, EST) and by endoscopy patients take stone, respectively, in the preoperative1h, postoperative6h, postoperative24h, in48h extraction hollow venous blood3ml, at the same time testing the four points in time amylase, lipase and c-reactive protein (C-reactive protein, CRP), statistical comparison. Will the postoperatie ERCP abdominal pain, nausea, vomiting, abdominal or on the left upper abdominal tenderness, the symptoms and signs for24hours, and serum amylase three times higher than normal cap (420U/L) is defined as the postoperative pancreatitis ERCP (post-ERCP pancreatitis, PEP), and the postoperative patients into I group (PEP group) and â…¡ group (the PEP group). The application of statistics SPSS17.0software, to two groups of the amylase, lipase,CRP and comparison, measurement data two separate t test sample inspection. P<0.05think with a statistical significance.Conclusion:CRP can and serum amylase, lipase combined determination, as the early diagnosis of acute pancreatitis ERCP indexes, and through the determination of CRP, may to the severity of postoperative pancreatitis ERCP forecast and evaluation...