The Research Of The Amount Of Oral Poisoning On Acute Paraquat Poisoning

Objective: Through summarize the statistical data of the assessment ofthe amount of oral poisoning, the reproduction of poison quantity, bloodtoxicant concentration and prognosis of patients with paraquat poisoning by2010,as well as the determination of the oral capacity and2011oral capacityof the normal population and assumptions simulated poison amount ofdetermination, were compared from the gender, age, height, weight,season,and other aspects, to discuss whether there is the existence ofdifferences or not in the impact of oral capacity with such many related factors,and thus speculate the simulation of oral quantity in different crowd, toprovide the theoretical basis for clinical prevention and treatment, so as toachieve the purpose of improving patients' prognosis.Methods:1Selected60patients with oral paraquat poisoning as research object in theemergency department of the Second Hospital of Hebei Medical University in2010, each30people between man and woman. A retrospective study on theassessment method, the assessment of the oral amount of poison (theassessment of the oral poisoning according to the words of patients afterarriving at hospital), the reproduction of the poison quantity (to reproduce theoral poisoning quantity using mineral water and to collect in the measuringcup for the determination), blood toxicant concentration and prognosis werecompared to judge the statistical difference (P <0.05),with the comparability.Using SPSS13statistical software package for statistical analysis, all data bynormal inspection normal count data were the measurement data with themean±SD (x±s), were compared among groups using t test, the heterogeneityof variance t`test,if P <0.05,it thinks that there are differences, that wasstatistically significant. The relationship between the group does not meet the normal distribution using the spearman rank correlation analysis,if P <0.05,itthinks that there are differences, that was statistically significant.2Selected the health of the general population60as the object of study inspring and autumn2011to do their testing in accordance, on the basis ofcompletely randomized block principle, specific subgroups: Based on gendersubgroups for men and women; based on age were divided into the group A1between20-30, the group A2between30-40, the group A3between40-50, thegroup A4between50-60; based on height were divided into the group B1between150cm-160cm, the group B2between160cm-170cm, the group B3between170cm-180cm; based on weight were divided into the group C1between50-60kg, the group C2between60-70kg, the group C3between70-80kg; based on the seasons subgroups for spring(17degrees) and autumn(7degrees). The first single factor analysis from different gender, age, height,weight, season5indexes and oral capacity of the relationship, then thestatistical significance and may have clinical significance in multivariatefactor analysis. Using SPSS13statistical software package for statisticalanalysis, all data by normal inspection normal,the measurement data withthe mean±SD (x±s), were compared among groups using t`test, if P <0.05,itthinks that there are differences, that was statistically significant. Therelationship between the group does not meet the normal distribution using therank sum test,if P <0.05,it thinks that there are differences, that wasstatistically significant.Results:1To assess the amount of60cases,the range of3-120ml,with an average of55.28±26.85ml；to reproduce the60cases,the range of2-90ml,an average of37.23±16.78ml；t`=4.414,P=0.000<0.05statistically significant. Medicalpractitioners to assess the amount of patients to reproduce a significantdifference. Male to reproduce higher than women,t`=2.907,P=0.005<0.05statistically significant.Blood concentration and prognosis of the correlationcoefficient r=-0.392,P=0.002,statistically significant.2Compare oral capacity of different age groups,season groups,weight groups,all P>0.05,there were no differences,no statistical significance；compare analog poison amount of different age groups,season groups,weightgroups,all P>0.05,there were no differences,no statistical significance.3Gender and oral capacity： a male in the range of40-130ml,an average of88.57±27.28ml,the scope of the general population in29-100ml,an averageof47.21±23.21ml, a small range in10-48ml, with an average of20.42±12.36ml；women a range40-80ml,the average61.88±11.43ml,thescope of the general population in20-48ml,an average of30.31±10.42ml,asmall range in5-35ml,with an average of15.69±7.34ml. Men,a big mouthand the general population and women,both P<0.05,difference statisticallysignificant. Oral capacity of the different height groups(a big mouth,ordinarymouth),P<0.05,difference statistically significant,indicating the higher thegreater the oral capacity.Conclusions:1Assess the amount of the emergency physician experience and patient toreproduce the concentration of poison volume and blood of patients with acuteoral paraquat poisoning,and the prognosis,both can be used as the acute oralparaquat poisoning amount of judgment in accordance with the doctor topoison the amount of assessment should also take into account gender,heightfactors.2Through the measurement and analysis of the oral capacity of the normalpopulation,the gender impact of oral capacity,men, a big mouth,ordinarymouth bigger than women；height affect the oral capacity tallness oral greatercapacity；age,weight,season had no effect on the oral capacity the amouth ofa paraquat poisoning that is fatal danger is credible.