Improved Stability Of Paprika Red Encapsulated In Liposome

Paprika red is a kind of natural pigment. Paprika red is non-toxic and nutritional, but its low stability limits the application comparing with artificial pigment,. Application of liposome technology can enhance its stability. Experiments performed using response surface analysis method to find the optimum conditions of encapsulating paprika red into lipsomes and compared the degradation rate of the pigment which encapsulated into lipsomes and not encapsulated after the treatment of illumination.The results of optimizing test showed that the optimum conditions by the response surface method is:ratio of lipid/drug is22:1(paprika red=0.02g, lecithin=0.44g), ultrasonic time=12min, the amount of organic solvents=25mL. The results of illumination test showed that liposome without antioxidants play a very slight protective effect on the paprika red. On the other hand liposome with antioxidants can significantly improve the stability of the pigment. The paprika liposome containing0.1%VE,0.02%TBHQ and0.02%VE can decrease the degradation rate of pigment by32.1%,26.7%,4.4%, respectively.